Phenotype Images associated with this Allele - MGI

About Help FAQ

Phenotype Images associated with this Allele

Nomenclature

Symbol:	Yap1^tm1Hmc
Name:	yes-associated protein 1; targeted mutation 1, Helen McNeill
MGI ID:	MGI:5486298
Synonyms:	Yap^flox

Images for
Allele

Click images for details

Image	Caption	Genotypes involving this allele
Image	Caption	Allelic Composition	Genetic Background
	Abnormal kidney development in Yap1^tm1Hmc/Yap1^tm1Hmc Six2^{tm1(tTA,tetO-EGFP/cre)Amc}/Six2⁺ mice	Yap1^tm1Hmc/Yap1^tm1Hmc Six2^{tm1(tTA,tetO-EGFP/cre)Amc}/Six2⁺	involves: 129 * 129S6/SvEvTac * C57BL/6J * C57BL/6NCrl
	Abnormal nephron formation in Yap1^tm1Hmc/Yap1^tm1Hmc Six2^{tm1(tTA,tetO-EGFP/cre)Amc}/Six2⁺ mice	Yap1^tm1Hmc/Yap1^tm1Hmc Six2^{tm1(tTA,tetO-EGFP/cre)Amc}/Six2⁺	involves: 129 * 129S6/SvEvTac * C57BL/6J * C57BL/6NCrl
	Impaired nephron induction in Yap1^tm1Hmc/Yap1^tm1Hmc Six2^{tm1(tTA,tetO-EGFP/cre)Amc}/Six2⁺ mice	Yap1^tm1Hmc/Yap1^tm1Hmc Six2^{tm1(tTA,tetO-EGFP/cre)Amc}/Six2⁺	involves: 129 * 129S6/SvEvTac * C57BL/6J * C57BL/6NCrl
	S-shaped body is reduced in size in Yap1^tm1Hmc/Yap1^tm1Hmc Six2^{tm1(tTA,tetO-EGFP/cre)Amc}/Six2⁺ nephrons	Yap1^tm1Hmc/Yap1^tm1Hmc Six2^{tm1(tTA,tetO-EGFP/cre)Amc}/Six2⁺	involves: 129 * 129S6/SvEvTac * C57BL/6J * C57BL/6NCrl
	Nephrogenesis abnormalities in Wwtr1^tm1Hmc/Wwtr1^tm1Hmc Six2^{tm1(tTA,tetO-EGFP/cre)Amc}/Six2⁺, Yap1^tm1Hmc/Yap1^tm1Hmc Six2^{tm1(tTA,tetO-EGFP/cre)Amc}/Six2⁺ and double mutant mice	Yap1^tm1Hmc/Yap1^tm1Hmc Six2^{tm1(tTA,tetO-EGFP/cre)Amc}/Six2⁺	involves: 129 * 129S6/SvEvTac * C57BL/6J * C57BL/6NCrl
		Wwtr1^tm1Hmc/Wwtr1^tm1Hmc Six2^{tm1(tTA,tetO-EGFP/cre)Amc}/Six2⁺	involves: 129 * 129S1/Sv * 129X1/SvJ * C57BL/6J
	Loss of foot processes in Yap1^tm1Hmc/Yap1^tm1Hmc Six2^{tm1(tTA,tetO-EGFP/cre)Amc}/Six2⁺ mice	Yap1^tm1Hmc/Yap1^tm1Hmc Six2^{tm1(tTA,tetO-EGFP/cre)Amc}/Six2⁺	involves: 129 * 129S6/SvEvTac * C57BL/6J * C57BL/6NCrl
	Decreased branching morphogenesis in Yap1^tm1Hmc/Yap1^tm1Hmc Six2^{tm1(tTA,tetO-EGFP/cre)Amc}/Six2⁺ kidneys	Yap1^tm1Hmc/Yap1^tm1Hmc Six2^{tm1(tTA,tetO-EGFP/cre)Amc}/Six2⁺	involves: 129 * 129S6/SvEvTac * C57BL/6J * C57BL/6NCrl

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/12/2024 MGI 6.24