About   Help   FAQ
Phenotype Images associated with this Allele
Nomenclature
Symbol: Adamts6b2b2182Clo
Name: ADAM metallopeptidase with thrombospondin type 1 motif 6; Bench to Bassinet Program (B2B/CVDC), mutation 2182 Cecilia Lo
MGI ID: MGI:5491254
Synonyms: Heimlich
Images for
Allele
Click images for details
Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Mutant 2182-003-1 (E15.5) has a dilated pulmonary artery and an overriding aorta diagnosed by EFIC imagingAdamts6b2b2182Clo/Adamts6b2b2182CloC57BL/6J-Adamts6b2b2182Clo
EFIC SummaryAdamts6b2b2182Clo/Adamts6b2b2182CloC57BL/6J-Adamts6b2b2182Clo
Serial 2D EFIC image stack in the coronal plane of 2182-003-1 (E15.5) shows overriding aorta, AVSD, and biventricular hypertrophy
Click thumbnail to play movie.
Adamts6b2b2182Clo/Adamts6b2b2182CloC57BL/6J-Adamts6b2b2182Clo
Mutant 2182-003-1 (E15.1) presents with abnormally attached hindlimbs, short snout, dome-shaped head, micrognathia, and slight hydropsAdamts6b2b2182Clo/Adamts6b2b2182CloC57BL/6J-Adamts6b2b2182Clo
Mutant 2182-003-1 (E15.5) exhibits a hypoplastic thymusAdamts6b2b2182Clo/Adamts6b2b2182CloC57BL/6J-Adamts6b2b2182Clo
Mutant 2182-003-2 (E15.5) presents with abnormally attached hindlimbs, short snout, dome-shaped head, and slight hydropsAdamts6b2b2182Clo/Adamts6b2b2182CloC57BL/6J-Adamts6b2b2182Clo
Mutant 2182-003-2 (E15.5) has a cleft palateAdamts6b2b2182Clo/Adamts6b2b2182CloC57BL/6J-Adamts6b2b2182Clo
Mutant 2182-003-2 (E15.5) shows a hypoplastic thymusAdamts6b2b2182Clo/Adamts6b2b2182CloC57BL/6J-Adamts6b2b2182Clo
Mutant 2182-003-2 (E15.5) exhibits malaligned great arteries, and shown to have DORV by EFIC imagingAdamts6b2b2182Clo/Adamts6b2b2182CloC57BL/6J-Adamts6b2b2182Clo
EFIC SummaryAdamts6b2b2182Clo/Adamts6b2b2182CloC57BL/6J-Adamts6b2b2182Clo
Serial 2D EFIC image stack in the coronal plane of 2182-003-2 (E15.5) exhibits DORV, AVSD, and biventricular hypertrophy
Click thumbnail to play movie.
Adamts6b2b2182Clo/Adamts6b2b2182CloC57BL/6J-Adamts6b2b2182Clo

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
11/12/2024
MGI 6.24
The Jackson Laboratory