![](https://www.informatics.jax.org/webshare/fetch_pixels.cgi?id=442126) | Mutant 2187-004-NC has a hypoplastic aorta and pulmonary stenosis as well as DORV and biventricular hypertrophy that was confirmed by EFIC imaging | b2b2187Clo/b2b2187Clo | C57BL/6J-b2b2187Clo |
Adamts6b2b2187.1Clo/Adamts6b2b2187.1Clo | C57BL/6J-Adamts6b2b2187.1Clo |
![](https://www.informatics.jax.org/webshare/fetch_pixels.cgi?id=442128) | EFIC Summary | b2b2187Clo/b2b2187Clo | C57BL/6J-b2b2187Clo |
Adamts6b2b2187.1Clo/Adamts6b2b2187.1Clo | C57BL/6J-Adamts6b2b2187.1Clo |
![](https://www.informatics.jax.org/webshare/fetch_pixels.cgi?id=442130) | Serial 2D EFIC image stack in the coronal plane of 2187-004-NC shows DORV, subaortic VSD, and biventricular hypertrophy Click thumbnail to play movie. | b2b2187Clo/b2b2187Clo | C57BL/6J-b2b2187Clo |
Adamts6b2b2187.1Clo/Adamts6b2b2187.1Clo | C57BL/6J-Adamts6b2b2187.1Clo |
![](https://www.informatics.jax.org/webshare/fetch_pixels.cgi?id=442132) | Mutant 2187-004-NC exhibits a short snout, micrognathia, and abnormal flexure of the hindlimb | b2b2187Clo/b2b2187Clo | C57BL/6J-b2b2187Clo |
Adamts6b2b2187.1Clo/Adamts6b2b2187.1Clo | C57BL/6J-Adamts6b2b2187.1Clo |
![](https://www.informatics.jax.org/webshare/fetch_pixels.cgi?id=442136) | Mutant 2187-004-NC has a cleft palate | b2b2187Clo/b2b2187Clo | C57BL/6J-b2b2187Clo |
Adamts6b2b2187.1Clo/Adamts6b2b2187.1Clo | C57BL/6J-Adamts6b2b2187.1Clo |
![](https://www.informatics.jax.org/webshare/fetch_pixels.cgi?id=442138) | Mutant 2187-004-NC shows an unfused sternum | b2b2187Clo/b2b2187Clo | C57BL/6J-b2b2187Clo |
Adamts6b2b2187.1Clo/Adamts6b2b2187.1Clo | C57BL/6J-Adamts6b2b2187.1Clo |
![](https://www.informatics.jax.org/webshare/fetch_pixels.cgi?id=442134) | Mutant 2187-004-NC exhibits a hypoplastic thymus | b2b2187Clo/b2b2187Clo | C57BL/6J-b2b2187Clo |
Adamts6b2b2187.1Clo/Adamts6b2b2187.1Clo | C57BL/6J-Adamts6b2b2187.1Clo |
![](https://www.informatics.jax.org/webshare/fetch_pixels.cgi?id=443267) | Mutant 2187-004-1 (E16.5) has hydrocephalus, build up of blood in the brain, and hydrops when it was collected | b2b2187Clo/b2b2187Clo | C57BL/6J-b2b2187Clo |
Adamts6b2b2187.1Clo/Adamts6b2b2187.1Clo | C57BL/6J-Adamts6b2b2187.1Clo |
![](https://www.informatics.jax.org/webshare/fetch_pixels.cgi?id=442146) | Mutant 2187-004-1 (E16.5) exhibits pulmonary stenosis and double outlet right ventricle (DORV) that confirmed EFIC histology | b2b2187Clo/b2b2187Clo | C57BL/6J-b2b2187Clo |
Adamts6b2b2187.1Clo/Adamts6b2b2187.1Clo | C57BL/6J-Adamts6b2b2187.1Clo |
![](https://www.informatics.jax.org/webshare/fetch_pixels.cgi?id=442148) | EFIC Summary | b2b2187Clo/b2b2187Clo | C57BL/6J-b2b2187Clo |
Adamts6b2b2187.1Clo/Adamts6b2b2187.1Clo | C57BL/6J-Adamts6b2b2187.1Clo |
![](https://www.informatics.jax.org/webshare/fetch_pixels.cgi?id=442150) | Serial 2D EFIC image stack in the coronal plane of 2187-004-1 (E16.5) shows double outlet right ventricle (DORV), subaortic VSD, small LV, atrioventricular valve dysplasia, semilunar valve dysplasia, bicuspid aortic valve, and a spongy right ventricle Click thumbnail to play movie. | b2b2187Clo/b2b2187Clo | C57BL/6J-b2b2187Clo |
Adamts6b2b2187.1Clo/Adamts6b2b2187.1Clo | C57BL/6J-Adamts6b2b2187.1Clo |
![](https://www.informatics.jax.org/webshare/fetch_pixels.cgi?id=442154) | Color flow spectral Doppler imaging of mutant fetus 2187-004-1 (E16.5) in the transverse view shows aliasing with increased blood flow through inflow tracts, suggesting atrioventricular valve stenosis | b2b2187Clo/b2b2187Clo | C57BL/6J-b2b2187Clo |
Adamts6b2b2187.1Clo/Adamts6b2b2187.1Clo | C57BL/6J-Adamts6b2b2187.1Clo |
![](https://www.informatics.jax.org/webshare/fetch_pixels.cgi?id=442156) | Color flow spectral Doppler imaging of mutant fetus 2187-004-1 (E16.5) in the sagittal view shows aliasing with increased velocity of blood flow in pulmonary artery (PA), suggesting pulmonary stenosis | b2b2187Clo/b2b2187Clo | C57BL/6J-b2b2187Clo |
Adamts6b2b2187.1Clo/Adamts6b2b2187.1Clo | C57BL/6J-Adamts6b2b2187.1Clo |
![](https://www.informatics.jax.org/webshare/fetch_pixels.cgi?id=442158) | Spectral Doppler imaging of mutant fetus 2187-00401 (E16.5) in the sagittal view detects increased velocity of blood flow in pulmonary artery (PA), suggesting pulmonary stenosis, which is consistent with the findings of color flow imaging | b2b2187Clo/b2b2187Clo | C57BL/6J-b2b2187Clo |
Adamts6b2b2187.1Clo/Adamts6b2b2187.1Clo | C57BL/6J-Adamts6b2b2187.1Clo |
![](https://www.informatics.jax.org/webshare/fetch_pixels.cgi?id=442174) | Mutant 2187-006-2 (E15.5) has hindlimbs with abnormal flexure and hydrops | b2b2187Clo/b2b2187Clo | C57BL/6J-b2b2187Clo |
Adamts6b2b2187.1Clo/Adamts6b2b2187.1Clo | C57BL/6J-Adamts6b2b2187.1Clo |
![](https://www.informatics.jax.org/webshare/fetch_pixels.cgi?id=442176) | EFIC Summary | b2b2187Clo/b2b2187Clo | C57BL/6J-b2b2187Clo |
Adamts6b2b2187.1Clo/Adamts6b2b2187.1Clo | C57BL/6J-Adamts6b2b2187.1Clo |
![](https://www.informatics.jax.org/webshare/fetch_pixels.cgi?id=442178) | Serial 2D EFIC image stack in the coronal plane of 2187-006-2 (E15.5) shows overriding aorta, pmVSD, mild hypoplastic aorta, and biventricular hypertrophy Click thumbnail to play movie. | b2b2187Clo/b2b2187Clo | C57BL/6J-b2b2187Clo |
Adamts6b2b2187.1Clo/Adamts6b2b2187.1Clo | C57BL/6J-Adamts6b2b2187.1Clo |
![](https://www.informatics.jax.org/webshare/fetch_pixels.cgi?id=442188) | EFIC Summary | b2b2187Clo/b2b2187Clo | C57BL/6J-b2b2187Clo |
Adamts6b2b2187.1Clo/Adamts6b2b2187.1Clo | C57BL/6J-Adamts6b2b2187.1Clo |
![](https://www.informatics.jax.org/webshare/fetch_pixels.cgi?id=442190) | Serial 2D EFIC image stack in the coronal plane of 2187-006-4 (E15.5) shows overriding aorta, perimembranous VSD (pmVSD), muscular VSD (mVSD), and biventricular hypertrophy Click thumbnail to play movie. | b2b2187Clo/b2b2187Clo | C57BL/6J-b2b2187Clo |
Adamts6b2b2187.1Clo/Adamts6b2b2187.1Clo | C57BL/6J-Adamts6b2b2187.1Clo |
![](https://www.informatics.jax.org/webshare/fetch_pixels.cgi?id=442144) | Mutant 2187-004-NA presents with an unfused sternum | b2b2187Clo/b2b2187Clo | C57BL/6J-b2b2187Clo |
Adamts6b2b2187.1Clo/Adamts6b2b2187.1Clo | C57BL/6J-Adamts6b2b2187.1Clo |
![](https://www.informatics.jax.org/webshare/fetch_pixels.cgi?id=442142) | Mutant 2187-004-NC exhibits thymus hypoplasia | b2b2187Clo/b2b2187Clo | C57BL/6J-b2b2187Clo |
Adamts6b2b2187.1Clo/Adamts6b2b2187.1Clo | C57BL/6J-Adamts6b2b2187.1Clo |
![](https://www.informatics.jax.org/webshare/fetch_pixels.cgi?id=442140) | Mutant 2187-004-NA has a dilated pulmonary and malaligned great arteries, which is shown by EFIC histology to comprise double outlet right ventricle (DORV), and possible biventricular hypertrophy | b2b2187Clo/b2b2187Clo | C57BL/6J-b2b2187Clo |
Adamts6b2b2187.1Clo/Adamts6b2b2187.1Clo | C57BL/6J-Adamts6b2b2187.1Clo |
![](https://www.informatics.jax.org/webshare/fetch_pixels.cgi?id=443269) | EFIC Summary | b2b2187Clo/b2b2187Clo | C57BL/6J-b2b2187Clo |
Adamts6b2b2187.1Clo/Adamts6b2b2187.1Clo | C57BL/6J-Adamts6b2b2187.1Clo |
![](https://www.informatics.jax.org/webshare/fetch_pixels.cgi?id=443271) | Serial 2D EFIC image stack in the coronal plane of 2187-004-NA shows overriding aorta and pmVSD Click thumbnail to play movie. | b2b2187Clo/b2b2187Clo | C57BL/6J-b2b2187Clo |
Adamts6b2b2187.1Clo/Adamts6b2b2187.1Clo | C57BL/6J-Adamts6b2b2187.1Clo |
![](https://www.informatics.jax.org/webshare/fetch_pixels.cgi?id=442194) | Mutant 2187-004-NB shows biventricular hypertrophy confirmed by MRI imaging | b2b2187Clo/b2b2187Clo | C57BL/6J-b2b2187Clo |
b2b2187.2Clo/b2b2187.2Clo | C57BL/6J-b2b2187.2Clo |
![](https://www.informatics.jax.org/webshare/fetch_pixels.cgi?id=442196) | Serial micro-MRI image stack in the coronal plane of 2287-004-NB reveals ventricular hypertrophy Click thumbnail to play movie. | b2b2187Clo/b2b2187Clo | C57BL/6J-b2b2187Clo |
b2b2187.2Clo/b2b2187.2Clo | C57BL/6J-b2b2187.2Clo |
![](https://www.informatics.jax.org/webshare/fetch_pixels.cgi?id=442200) | Mutant 2187-007-NC has biventricular hypertrophy also seen by MRI | b2b2187Clo/b2b2187Clo | C57BL/6J-b2b2187Clo |
b2b2187.2Clo/b2b2187.2Clo | C57BL/6J-b2b2187.2Clo |
![](https://www.informatics.jax.org/webshare/fetch_pixels.cgi?id=442204) | Mutant 2187-007-NC shows a cleft palate | b2b2187Clo/b2b2187Clo | C57BL/6J-b2b2187Clo |
b2b2187.2Clo/b2b2187.2Clo | C57BL/6J-b2b2187.2Clo |
![](https://www.informatics.jax.org/webshare/fetch_pixels.cgi?id=442206) | Mutant 2187-007-NC presents with micrognathia and microphthalmia | b2b2187Clo/b2b2187Clo | C57BL/6J-b2b2187Clo |
b2b2187.2Clo/b2b2187.2Clo | C57BL/6J-b2b2187.2Clo |
![](https://www.informatics.jax.org/webshare/fetch_pixels.cgi?id=442202) | Serial micro-MRI image stack in the coronal plane of 2287-007-NC reveals ventricular hypertrophy Click thumbnail to play movie. | b2b2187Clo/b2b2187Clo | C57BL/6J-b2b2187Clo |
b2b2187.2Clo/b2b2187.2Clo | C57BL/6J-b2b2187.2Clo |
![](https://www.informatics.jax.org/webshare/fetch_pixels.cgi?id=442313) | Mutant 2187-006-1 (E15.5) exhibits biventricular hypertrophy diagnosed by EFIC histology | b2b2187Clo/b2b2187Clo | C57BL/6J-b2b2187Clo |
b2b2187.2Clo/b2b2187.2Clo | C57BL/6J-b2b2187.2Clo |
![](https://www.informatics.jax.org/webshare/fetch_pixels.cgi?id=442315) | EFIC Summary | b2b2187Clo/b2b2187Clo | C57BL/6J-b2b2187Clo |
b2b2187.2Clo/b2b2187.2Clo | C57BL/6J-b2b2187.2Clo |
![](https://www.informatics.jax.org/webshare/fetch_pixels.cgi?id=442198) | Serial 2D EFIC image stack in the coronal plane of 2187-006-1 (E15.5) shows biventricular hypertrophy Click thumbnail to play movie. | b2b2187Clo/b2b2187Clo | C57BL/6J-b2b2187Clo |
b2b2187.2Clo/b2b2187.2Clo | C57BL/6J-b2b2187.2Clo |