Phenotype Images associated with this Allele - MGI

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Phenotype Images associated with this Allele

Nomenclature

Symbol:	Adamts6^b2b2228Clo
Name:	ADAM metallopeptidase with thrombospondin type 1 motif 6; Bench to Bassinet Program (B2B/CVDC), mutation 2228 Cecilia Lo
MGI ID:	MGI:5491258
Synonyms:	Willy

Images for
Allele

Click images for details

Image	Caption	Genotypes involving this allele
Image	Caption	Allelic Composition	Genetic Background
	Mutant 2228-006-2 (E16.5) exhibits malalignment of the great arteries with a hypoplastic aorta	Adamts6^b2b2228Clo/Adamts6^b2b2228Clo	C57BL/6J-Adamts6^b2b2228Clo
	EFIC Summary	Adamts6^b2b2228Clo/Adamts6^b2b2228Clo	C57BL/6J-Adamts6^b2b2228Clo
	Serial 2D EFIC image stack in the coronal plane of mutant 2228-006-2 (E16.5) has DORV, AVSD, and hypoplastic aorta Click thumbnail to play movie.	Adamts6^b2b2228Clo/Adamts6^b2b2228Clo	C57BL/6J-Adamts6^b2b2228Clo
	Mutant 2228-006-2 (E16.5) exhibits abnormal flexure of the hindlimbs and a short snout	Adamts6^b2b2228Clo/Adamts6^b2b2228Clo	C57BL/6J-Adamts6^b2b2228Clo
	Mutant 2228-006-2 (E16.5) has hypoplastic thymus	Adamts6^b2b2228Clo/Adamts6^b2b2228Clo	C57BL/6J-Adamts6^b2b2228Clo
	Mutant 2228-004-1 (E14.5) presents with a short snout, abnormal flexure of the hindlimbs, and hydrops	Adamts6^b2b2228Clo/Adamts6^b2b2228Clo	C57BL/6J-Adamts6^b2b2228Clo
	Mutant 2228-004-1 (E14.5) exhibits a cleft palate	Adamts6^b2b2228Clo/Adamts6^b2b2228Clo	C57BL/6J-Adamts6^b2b2228Clo
	Mutant 2228-004-1 (E14.5) exhibits a hypoplastic thymus	Adamts6^b2b2228Clo/Adamts6^b2b2228Clo	C57BL/6J-Adamts6^b2b2228Clo
	Mutant 2228-004-1 (E14.5) has a slightly abnormal arrangement of the great arteries; the pulmonary is further to the left, confirmed to be DORV by EFIC imaging	Adamts6^b2b2228Clo/Adamts6^b2b2228Clo	C57BL/6J-Adamts6^b2b2228Clo
	EFIC Summary	Adamts6^b2b2228Clo/Adamts6^b2b2228Clo	C57BL/6J-Adamts6^b2b2228Clo
	Serial 2D EFIC image stack in of 2228-004-1 (E14.5) in the the coronal plane shows DORV and subaortic VSD Click thumbnail to play movie.	Adamts6^b2b2228Clo/Adamts6^b2b2228Clo	C57BL/6J-Adamts6^b2b2228Clo

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