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Phenotype Images associated with this Allele
Nomenclature
Symbol: Dnah11b2b2349Clo
Name: dynein, axonemal, heavy chain 11; Bench to Bassinet Program (B2B/CVDC) mutation 2349, Cecilia Lo
MGI ID: MGI:5491272
Synonyms: CrissCross
Images for
Allele
Click images for details
Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Mutant 2249-002-LA exhibits situs inversus totalis with dextrocardia, inverted outflow, inverted lung and liver lobation, and dextrogastriaDnah11b2b2349Clo/Dnah11b2b2349CloC57BL/6J-Dnah11b2b2349Clo
Serial 2D EFIC image stack in the coronal plane of 2349-002-LA (E15.5) shows mirror image dextrocardia and mLV hypertrophy
Click thumbnail to play movie.		Dnah11b2b2349Clo/Dnah11b2b2349CloC57BL/6J-Dnah11b2b2349Clo
EFIC SummaryDnah11b2b2349Clo/Dnah11b2b2349CloC57BL/6J-Dnah11b2b2349Clo
Mutant 2349-003-NA exhibits hertrotaxy with dextrocardia, ambiguous lung lobation and dextrogastriaDnah11b2b2349Clo/Dnah11b2b2349CloC57BL/6J-Dnah11b2b2349Clo
EFIC SummaryDnah11b2b2349Clo/Dnah11b2b2349CloC57BL/6J-Dnah11b2b2349Clo
Serial 2D EFIC image stack in the coronal plane of 2349-003-NA shows mirror image dextrocardia and mLV hypertrophy
Click thumbnail to play movie.		Dnah11b2b2349Clo/Dnah11b2b2349CloC57BL/6J-Dnah11b2b2349Clo
Mutant 2349-003-NA exhibits heterotaxy with inverted liver lobationDnah11b2b2349Clo/Dnah11b2b2349CloC57BL/6J-Dnah11b2b2349Clo
Mutant 2349-003-NA has hypoplastic spleenDnah11b2b2349Clo/Dnah11b2b2349CloC57BL/6J-Dnah11b2b2349Clo
Mutant 2349-003-NA shows malaligned sternal vertebraeDnah11b2b2349Clo/Dnah11b2b2349CloC57BL/6J-Dnah11b2b2349Clo
Mutant 2349-002-LB presents with situs inverses totalis with dextrogastriaDnah11b2b2349Clo/Dnah11b2b2349CloC57BL/6J-Dnah11b2b2349Clo
Mutant 2349-002-LB has situs inversus totalis with dextrogastriaDnah11b2b2349Clo/Dnah11b2b2349CloC57BL/6J-Dnah11b2b2349Clo
Mutant 2349-003-LB exhibits a malaligned sternal vertebraeDnah11b2b2349Clo/Dnah11b2b2349CloC57BL/6J-Dnah11b2b2349Clo
Mutant 2349-002-LB shows immotile airway cilia
Click thumbnail to play movie.		Dnah11b2b2349Clo/Dnah11b2b2349CloC57BL/6J-Dnah11b2b2349Clo
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory