Phenotype Images associated with this Allele - MGI

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Phenotype Images associated with this Allele

Nomenclature

Symbol:	Arhgef12^tm1Sgkd
Name:	Rho guanine nucleotide exchange factor 12; targeted mutation 1, Silvio Gutkind
MGI ID:	MGI:5505411
Synonyms:	Larg^-

Images for
Allele

Click images for details

Image	Caption	Genotypes involving this allele
Image	Caption	Allelic Composition	Genetic Background
	Arhgef11^tm1Sgkd/Arhgef11^tm1Sgkd Arhgef12^tm1Sgkd/Arhgef12^tm1Sgkd embryos are less developed with partial branching failure of the cranial vessels	Arhgef11^tm1Sgkd/Arhgef11^tm1Sgkd Arhgef12^tm1Sgkd/Arhgef12^tm1Sgkd	involves: 129 * C57BL/6J
	Placentas of double Arhgef11^tm1Sgkd and Arhgef12^tm1Sgkd homozygous embryos are less developed and poorly vascularized	Arhgef11^tm1Sgkd/Arhgef11^tm1Sgkd Arhgef12^tm1Sgkd/Arhgef12^tm1Sgkd	involves: 129 * C57BL/6J

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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