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Phenotype Images associated with this Allele
Nomenclature
Symbol: b2b2289Clo
Name: Mutant line 2289; Bench to Bassinet Program (B2B/CVDC), mutation 2289 Cecilia Lo
MGI ID: MGI:5510163
Synonyms: Archie
Images for
Allele
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Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Mutant 2289-004-2 (16.5) has hypoplastic aorta and double outlet right ventricle (DORV)b2b2289Clo/b2b2289CloC57BL/6J-b2b2289Clo
Serial 2D EFIC image stack in the coronal plane of 2289-004-2 (E16.5) reveals DORV, subaortic VSD, mild hypoplastic aortic arch, and thick AV valves
Click thumbnail to play movie.
b2b2289Clo/b2b2289CloC57BL/6J-b2b2289Clo
EFIC Summaryb2b2289Clo/b2b2289CloC57BL/6J-b2b2289Clo
Mutant 2289-004-2 (E16.5) presents with hydronephrosis and possible cystic kidneysb2b2289Clo/b2b2289CloC57BL/6J-b2b2289Clo
Mutant 2289-004-2 has small tubular cystsb2b2289Clo/b2b2289CloC57BL/6J-b2b2289Clo
Mutant 2289-004-3 (E16.5) presents with DORV, hypoplastic transverse arch, and vascular ringb2b2289Clo/b2b2289CloC57BL/6J-b2b2289Clo
Serial 2D EFIC image stack in the coronal plane of 2289-004-3 (E16.5) reveals DORV, subaortic VSD, RAA, hypoplastic transverse aorta forming vascular ring, anomalous connection from aorta to PDA, anomalous left subclavian artery arising from the descending aorta, abnormal systemic vasculature (right SVC connects to left SVC)
Click thumbnail to play movie.
b2b2289Clo/b2b2289CloC57BL/6J-b2b2289Clo
EFIC Summaryb2b2289Clo/b2b2289CloC57BL/6J-b2b2289Clo
Mutant 2289-004-3 (E16.5) has hydronephrosisb2b2289Clo/b2b2289CloC57BL/6J-b2b2289Clo

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/19/2024
MGI 6.24
The Jackson Laboratory