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Phenotype Images associated with this Allele
Nomenclature
Symbol: Nlrp3tm3.1Hhf
Name: NLR family, pyrin domain containing 3; targeted mutation 3.1, Hal M Hoffman
MGI ID: MGI:5517707
Synonyms: D301N NLRP3, NOMID
Images for
Allele
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Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Nlrp3tm3.1Hhf/Nlrp3+ mice display joint inflammationNlrp3tm3.1Hhf/Nlrp3+involves: 129
Nlrp3tm3.1Hhf/Nlrp3+ mice exhibit stunted skeletal growth and reduced bone massNlrp3tm3.1Hhf/Nlrp3+involves: 129
Nlrp3tm3.1Hhf/Nlrp3+ mice exhibit disorganized growth platesNlrp3tm3.1Hhf/Nlrp3+involves: 129
Nlrp3tm3.1Hhf/Nlrp3+ mice exhibit increased bone resorptionNlrp3tm3.1Hhf/Nlrp3+involves: 129
Osteoclast differentiation is increased in Nlrp3tm3.1Hhf/Nlrp3+ miceNlrp3tm3.1Hhf/Nlrp3+involves: 129
Evidence of meningitis in Nlrp3tm3.1Hhf/Nlrp3+ miceNlrp3tm3.1Hhf/Nlrp3+involves: 129
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory