Phenotype Images associated with this Allele - MGI

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Phenotype Images associated with this Allele

Nomenclature

Symbol:	Sox11^tm1.1Gan
Name:	SRY (sex determining region Y)-box 11; targeted mutation 1.1, Lin Gan
MGI ID:	MGI:5518640
Synonyms:	Sox11^loxP

Images for
Allele

Click images for details

Image	Caption	Genotypes involving this allele
Image	Caption	Allelic Composition	Genetic Background
	Sox11^tm1.1Gan/Sox11^tm1.1Gan Tg(EIIa-cre)C5379Lmgd/0 mutants display cleft palate with retardation to palatal shelf elevation	Sox11^tm1.1Gan/Sox11^tm1.1Gan Tg(EIIa-cre)C5379Lmgd/0	involves: 129S6/SvEvTac * C57BL/6 * FVB/N
	Shorter mandible and displaced tongue position obstructs palatal elevation in Sox11^tm1.1Gan/Sox11^tm1.1Gan Tg(EIIa-cre)C5379Lmgd/0 mutants	Sox11^tm1.1Gan/Sox11^tm1.1Gan Tg(EIIa-cre)C5379Lmgd/0	involves: 129S6/SvEvTac * C57BL/6 * FVB/N
	Cell proliferation in the mandibular mesenchyme is reduced in Sox11^tm1.1Gan/Sox11^tm1.1Gan Tg(EIIa-cre)C5379Lmgd/0 embryos	Sox11^tm1.1Gan/Sox11^tm1.1Gan Tg(EIIa-cre)C5379Lmgd/0	involves: 129S6/SvEvTac * C57BL/6 * FVB/N
	Cell proliferation of the palatal shelf is reduced in Sox11^tm1.1Gan/Sox11^tm1.1Gan Tg(EIIa-cre)C5379Lmgd/0 mice	Sox11^tm1.1Gan/Sox11^tm1.1Gan Tg(EIIa-cre)C5379Lmgd/0	involves: 129S6/SvEvTac * C57BL/6 * FVB/N
	Decrease in retinal ganglion cells in single Sox11^tm1.1Gan and Sox4^tm1Vlf homozygous conditional mutants and abolishment of retinal ganglion cells in Sox11^tm1.1Gan/Sox11^tm1.1Gan Sox4^tm1Vlf/Sox4^tm1Vlf Tg(Six3-cre)69Frty/0 retinas	Sox11^tm1.1Gan/Sox11^tm1.1Gan Tg(Six3-cre)69Frty/0	involves: 129S6/SvEvTac * C57BL/6 * C57BL/6J * DBA/2
		Sox11^tm1.1Gan/Sox11^tm1.1Gan Sox4^tm1Vlf/Sox4^tm1Vlf Tg(Six3-cre)69Frty/0	involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6 * DBA/2
		Sox4^tm1Vlf/Sox4^tm1Vlf Tg(Six3-cre)69Frty/0	involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * C57BL/6J * DBA/2

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