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Phenotype Images associated with this Allele
Nomenclature
Symbol: Fat1tm1.2Fhel
Name: FAT atypical cadherin 1; targeted mutation 1.2, Francoise Helmbacher
MGI ID: MGI:5524121
Synonyms: Fat1deltaTM
Images for
Allele
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Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Reduced cutaneous maximus muscle at E12.5 leads to misshaped cutaenous maximus and presence of ectopic muscles in the shoulder of Fat1tm1.2Fhel/Fat1tm1.2Fhel Tg(Myl1-lacZ)1Ibdml/0 miceFat1tm1.2Fhel/Fat1tm1.2Fhel
Tg(Myl1-lacZ)1Ibdml/0		involves: 129S6/SvEvTac * BALB/cJ * C57BL/6J * SJL
Shapes of selective facial and scapulohumeral muscles are altered in Fat1tm1.2Fhel/Fat1tm1.2Fhel Tg(Myl1-lacZ)1Ibdml/0 fetusesFat1tm1.2Fhel/Fat1tm1.2Fhel
Tg(Myl1-lacZ)1Ibdml/0		involves: 129S6/SvEvTac * BALB/cJ * C57BL/6J * SJL
Reduced endolymphatic duct and endolymphatic sac in E12.5 Fat1tm1.2Fhel/Fat1tm1.2Fhel Tg(Myl1-lacZ)1Ibdml/0 embryo inner earsFat1Gt(KST249)Byg/Fat1Gt(KST249)Byg
Tg(Myl1-lacZ)1Ibdml/0		involves: 129P2/OlaHsd
Scapulohumeral muscle shape abnormalities in Fat1tm1Fhel/Fat1tm1Fhel Pax3tm1(cre)Joe/Pax3+ Tg(Myl1-lacZ)1Ibdml/0 embryosFat1tm1Fhel/Fat1tm1Fhel
Pax3tm1(cre)Joe/Pax3+
Tg(Myl1-lacZ)1Ibdml/0		involves: 129S6/SvEvTac * C57BL/6 * C57BL/6J * SJL
Fat1tm1.2Fhel/Fat1tm1.2Fhel Tg(Myl1-lacZ)1Ibdml/0 embryos show selective and asymmetric skeletal muscle shape abnormalitiesFat1tm1.2Fhel/Fat1tm1.2Fhel
Tg(Myl1-lacZ)1Ibdml/0		involves: 129S6/SvEvTac * BALB/cJ * C57BL/6J * SJL
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory