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Phenotype Images associated with this Allele
Nomenclature
Symbol: Ubr4tm1.2Nkt
Name: ubiquitin protein ligase E3 component n-recognin 4; targeted mutation 1.2, Yoshihiro Nakatani
MGI ID: MGI:5532332
Images for
Allele
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Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Mild growth retardation and brain abnormalities in Ubr4tm1.2Nkt/Ubr4tm1.2Nkt Edil3Tg(Sox2-cre)1Amc/0 embryosUbr4tm1.2Nkt/Ubr4tm1.2Nkt
Edil3Tg(Sox2-cre)1Amc/Edil3+
involves: 129S6/SvEvTac * C57BL/6 * CBA * SJL
Heart development abnormalities in Ubr4tm1.2Nkt/Ubr4tm1.2Nkt Edil3Tg(Sox2-cre)1Amc/0 miceUbr4tm1.2Nkt/Ubr4tm1.2Nkt
Edil3Tg(Sox2-cre)1Amc/Edil3+
involves: 129S6/SvEvTac * C57BL/6 * CBA * SJL
Proliferation defects in Ubr4tm1.2Nkt/Ubr4tm1.2Nkt Edil3Tg(Sox2-cre)1Amc/0 heartsUbr4tm1.2Nkt/Ubr4tm1.2Nkt
Edil3Tg(Sox2-cre)1Amc/Edil3+
involves: 129S6/SvEvTac * C57BL/6 * CBA * SJL
Abnormal liver in Ubr4tm1.2Nkt/Ubr4tm1.2Nkt Edil3Tg(Sox2-cre)1Amc/0 embryosUbr4tm1.2Nkt/Ubr4tm1.2Nkt
Edil3Tg(Sox2-cre)1Amc/Edil3+
involves: 129S6/SvEvTac * C57BL/6 * CBA * SJL
Abnormal brain development in Ubr4tm1.2Nkt/Ubr4tm1.2Nkt Edil3Tg(Sox2-cre)1Amc/0 embryosUbr4tm1.2Nkt/Ubr4tm1.2Nkt
Edil3Tg(Sox2-cre)1Amc/Edil3+
involves: 129S6/SvEvTac * C57BL/6 * CBA * SJL

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory