Phenotype Images associated with this Allele - MGI

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Phenotype Images associated with this Allele

Nomenclature

Symbol:	Csnk1a1^tm1.1Ybn
Name:	casein kinase 1, alpha 1; targeted mutation 1.1, Yinon Ben-Neriah
MGI ID:	MGI:5543667
Synonyms:	Csnk1a1^fl

Images for
Allele

Click images for details

Image	Caption	Genotypes involving this allele
Image	Caption	Allelic Composition	Genetic Background
	Csnk1a1^tm1.1Ybn/Csnk1a1^tm1.1Ybn Tg(KRT14-cre/ERT)20Efu/0 mice show skin hyperpigmentation of ears, paws, mouth, and trunk after tamoxifen treatment	Csnk1a1^tm1.1Ybn/Csnk1a1^tm1.1Ybn Tg(KRT14-cre/ERT)20Efu/0	involves: 129S1/Sv * 129X1/SvJ * CD-1
	Immunohistochemistry of paw skin in tamoxifen-treated Csnk1a1^tm1.1Ybn/Csnk1a1^tm1.1Ybn Tg(KRT14-cre/ERT)20Efu/0 mice	Csnk1a1^tm1.1Ybn/Csnk1a1^tm1.1Ybn Tg(KRT14-cre/ERT)20Efu/0	involves: 129S1/Sv * 129X1/SvJ * CD-1
	Topical treatment with tamoxifen for 14 days induces skin hyperpigmentation on the ear in Csnk1a1^tm1.1Ybn/Csnk1a1^tm1.1Ybn Tg(KRT14-cre/ERT)20Efu/0 mice	Csnk1a1^tm1.1Ybn/Csnk1a1^tm1.1Ybn Tg(KRT14-cre/ERT)20Efu/0	involves: 129S1/Sv * 129X1/SvJ * CD-1
	Skin hyperpigmentation in Csnk1a1^tm1.1Ybn/Csnk1a1^tm1.1Ybn Tg(KRT14-cre/ERT)20Efu/0 mice but not in Csnk1a1^tm1.1Ybn/Csnk1a1^tm1.1Ybn Trp53^tm1Brn/Trp53^tm1Brn Tg(KRT14-cre/ERT)20Efu/0 mice	Csnk1a1^tm1.1Ybn/Csnk1a1^tm1.1Ybn Tg(KRT14-cre/ERT)20Efu/0	involves: 129S1/Sv * 129X1/SvJ * CD-1
		Csnk1a1^tm1.1Ybn/Csnk1a1^tm1.1Ybn Trp53^tm1Brn/Trp53^tm1Brn Tg(KRT14-cre/ERT)20Efu/0	involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * CD-1
	Intradermal injection of an anti-Kit antibody (ACK2) decreases the number of melanocytes in the epidermis of Csnk1a1^tm1.1Ybn/Csnk1a1^tm1.1Ybn Tg(KRT14-cre/ERT)20Efu/0 (SKO) mice	Csnk1a1^tm1.1Ybn/Csnk1a1^tm1.1Ybn Tg(KRT14-cre/ERT)20Efu/0	involves: 129S1/Sv * 129X1/SvJ * CD-1
	Sunburn damage (swelling of the tail) after UVB exposure is not seen in eumelanized tails of Csnk1a1^tm1.1Ybn/Csnk1a1^tm1.1Ybn Tg(KRT14-cre/ERT)20Efu mice	Csnk1a1^tm1.1Ybn/Csnk1a1^tm1.1Ybn Tg(KRT14-cre/ERT)20Efu/0	involves: 129S1/Sv * 129X1/SvJ * CD-1

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