Phenotype Images associated with this Allele

Nomenclature

Symbol:	Dnah5^b2b2395Clo
Name:	dynein, axonemal, heavy chain 5; Bench to Bassinet Program (B2B/CVDC), mutation 2395 Cecilia Lo
MGI ID:	MGI:5552945
Synonyms:	Peaches

Images for
Allele

Click images for details

Image	Caption	Genotypes involving this allele
Image	Caption	Allelic Composition	Genetic Background
	Mutant 2395-006-LB presents with heterotaxy and dextrocardia with levogastria	Dnah5^b2b2395Clo/Dnah5^b2b2395Clo	C57BL/6J-Dnah5^b2b2395Clo
	EFIC Summary	Dnah5^b2b2395Clo/Dnah5^b2b2395Clo	C57BL/6J-Dnah5^b2b2395Clo
	Serial 2D EFIC stack in the coronal plane of 2395-006-LB shows mirror image dextrocardia {I,L,I}, pmVSD, and small mRV Click thumbnail to play movie.	Dnah5^b2b2395Clo/Dnah5^b2b2395Clo	C57BL/6J-Dnah5^b2b2395Clo
	Mutant 2395-006LB exhibits immotile cilia Click thumbnail to play movie.	Dnah5^b2b2395Clo/Dnah5^b2b2395Clo	C57BL/6J-Dnah5^b2b2395Clo
	Mutant 2395-006-LA has situs inversus totalis	Dnah5^b2b2395Clo/Dnah5^b2b2395Clo	C57BL/6J-Dnah5^b2b2395Clo
	Mutant 2395-006-LA has immotile cilia Click thumbnail to play movie.	Dnah5^b2b2395Clo/Dnah5^b2b2395Clo	C57BL/6J-Dnah5^b2b2395Clo
	Mutant 2395-006-LI presents with situs inversus totalis with dextrocardia and dextrogastria	Dnah5^b2b2395Clo/Dnah5^b2b2395Clo	C57BL/6J-Dnah5^b2b2395Clo
	Mutant 2395-006-LI shows immotile cilia Click thumbnail to play movie.	Dnah5^b2b2395Clo/Dnah5^b2b2395Clo	C57BL/6J-Dnah5^b2b2395Clo
	Mutant 2395-004-NA presents with microphthalmia, short snout, and micrognathia	Dnah5^b2b2395Clo/Dnah5^b2b2395Clo	C57BL/6J-Dnah5^b2b2395Clo
	Mutant 2395-004-NA exhibits a cleft palate	Dnah5^b2b2395Clo/Dnah5^b2b2395Clo	C57BL/6J-Dnah5^b2b2395Clo
	Mutant 2395-004-NA has a malaligned sternal vertebra	Dnah5^b2b2395Clo/Dnah5^b2b2395Clo	C57BL/6J-Dnah5^b2b2395Clo
	Mutant 2395-004-NA exhibits heterotaxy with dextrocardia, left lung isomerism (1R/1L), and dextrogastria	Dnah5^b2b2395Clo/Dnah5^b2b2395Clo	C57BL/6J-Dnah5^b2b2395Clo
	Mutant 2395-004-NA shows dextrocardia, ventricular hypertrophy, and pulmonary stenosis	Dnah5^b2b2395Clo/Dnah5^b2b2395Clo	C57BL/6J-Dnah5^b2b2395Clo
	Mutant 2395-004-NA has a duplex left kidney and cystic kidney	Dnah5^b2b2395Clo/Dnah5^b2b2395Clo	C57BL/6J-Dnah5^b2b2395Clo
	EFIC Summary	Dnah5^b2b2395Clo/Dnah5^b2b2395Clo	C57BL/6J-Dnah5^b2b2395Clo
	Serial EFIC image stack of 2395-004-NA in the coronal plane reveals dextrocardia {A, L, L(I)}, AVSD, anomalous coronary venous connected to left SVC, dual IVC, left atrial isomerism, biventricular hypertrophy, and left lung isomerism Click thumbnail to play movie.	Dnah5^b2b2395Clo/Dnah5^b2b2395Clo	C57BL/6J-Dnah5^b2b2395Clo
	Mutant 2395-004-NA has a duplex right kidney	Dnah5^b2b2395Clo/Dnah5^b2b2395Clo	C57BL/6J-Dnah5^b2b2395Clo
	Mutant 2395-004-NA has a duplex left kidney	Dnah5^b2b2395Clo/Dnah5^b2b2395Clo	C57BL/6J-Dnah5^b2b2395Clo

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