About   Help   FAQ
Phenotype Images associated with this Allele
Nomenclature
Symbol: Qrich1b2b2404Clo
Name: glutamine-rich 1; Bench to Bassinet Program (B2B/CVDC), mutation 2404 Cecilia Lo
MGI ID: MGI:5554436
Synonyms: Wycleft
Images for
Allele
Click images for details
Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Mutant 2404-002-3 (E15.5) has abnormal great artery arrangement associated with malrotation of the heart, and subsequently was shown to be DORV by EFIC imagingQrich1b2b2404Clo/Qrich1b2b2404CloC57BL/6J-Qrich1b2b2404Clo
EFIC SummaryQrich1b2b2404Clo/Qrich1b2b2404CloC57BL/6J-Qrich1b2b2404Clo
Serial 2D EFIC image stack in the coronal plane of 2404-002-3 (E15.5) reveals DORV and AVSD
Click thumbnail to play movie.		Qrich1b2b2404Clo/Qrich1b2b2404CloC57BL/6J-Qrich1b2b2404Clo
Color flow spectral Doppler imaging in the sagittal view of mutant 2404-004-2-3 (E15.5) shows the two great arteries predominantly originating from the RV, which suggests DORV
Click thumbnail to play movie.		Qrich1b2b2404Clo/Qrich1b2b2404CloC57BL/6J-Qrich1b2b2404Clo
Color flow spectral Doppler imaging of mutant 2404-002-3 (E15.5) in the sagittal view shows the shunting of AVSD
Click thumbnail to play movie.		Qrich1b2b2404Clo/Qrich1b2b2404CloC57BL/6J-Qrich1b2b2404Clo
Mutant 2404-002-3 (E15.5) was harvested with severe hydrops and abnormal vasculatureQrich1b2b2404Clo/Qrich1b2b2404CloC57BL/6J-Qrich1b2b2404Clo
Mutant 2404-002-3 (E15.5) has a cleft palateQrich1b2b2404Clo/Qrich1b2b2404CloC57BL/6J-Qrich1b2b2404Clo
Mutant 2404-002-3 (E15.5) has cystic kidneysQrich1b2b2404Clo/Qrich1b2b2404CloC57BL/6J-Qrich1b2b2404Clo
Kidneys of mutant 2404-002-3 have a few glomerular cystsQrich1b2b2404Clo/Qrich1b2b2404CloC57BL/6J-Qrich1b2b2404Clo
Mutant 2404-002-1 (E15.5) exhibits a cleft palateQrich1b2b2404Clo/Qrich1b2b2404CloC57BL/6J-Qrich1b2b2404Clo
Mutant 2404-002-1 (E15.5) presents with hypoplastic thymusQrich1b2b2404Clo/Qrich1b2b2404CloC57BL/6J-Qrich1b2b2404Clo
Mutant 2402-002-1 (E15.5) shows parallel outflow tracts and thin ventricles which is diagnosed as overriding aorta and ventricular non-compaction by EFIC imagingQrich1b2b2404Clo/Qrich1b2b2404CloC57BL/6J-Qrich1b2b2404Clo
EFIC SummaryQrich1b2b2404Clo/Qrich1b2b2404CloC57BL/6J-Qrich1b2b2404Clo
Serial 2D EFIC image stack in the coronal plane of 2404-002-1 reveals an overriding aorta, pmVSD, and ventricular non-compaction
Click thumbnail to play movie.		Qrich1b2b2404Clo/Qrich1b2b2404CloC57BL/6J-Qrich1b2b2404Clo
Mutant 2404-002-2 (E15.5) presents with a cleft palateQrich1b2b2404Clo/Qrich1b2b2404CloC57BL/6J-Qrich1b2b2404Clo
Mutant 2404-002-2 (E15.5) presents with parallel outflow tracts which is diagnosed as overriding aorta with EFIC imagingQrich1b2b2404Clo/Qrich1b2b2404CloC57BL/6J-Qrich1b2b2404Clo
Mutant 2404-002-2 (E15.5) appears to have cystic kidneysQrich1b2b2404Clo/Qrich1b2b2404CloC57BL/6J-Qrich1b2b2404Clo
EFIC SummaryQrich1b2b2404Clo/Qrich1b2b2404CloC57BL/6J-Qrich1b2b2404Clo
Serial 2D EFIC image stack in the coronal plane of 2404-002-2 (E15.5) reveals an overriding aorta, pmVSD, and ventricular non-compaction
Click thumbnail to play movie.		Qrich1b2b2404Clo/Qrich1b2b2404CloC57BL/6J-Qrich1b2b2404Clo
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
06/12/2024
MGI 6.13 		The Jackson Laboratory