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Phenotype Images associated with this Allele
Nomenclature
Symbol: Reep1tm1.1Cahb
Name: receptor accessory protein 1; targeted mutation 1.1, Christian Hubner
MGI ID: MGI:5558070
Images for
Allele
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Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Reep1tm1.1Cahb/Reep1tm1.1Cahb mice exhibit kyphosis and gait abnormalitiesReep1tm1.1Cahb/Reep1tm1.1Cahbinvolves: 129S1/Sv * 129X1/SvJ * C57BL/6
The gait phenotype of Reep1tm1.1Cahb/Reep1tm1.1Cahb mice is progressive, dose-dependent, and associated with a neurodegenerative rather than a neurodevelopmental pathology of upper motor neuron axonsReep1tm1.1Cahb/Reep1tm1.1Cahbinvolves: 129S1/Sv * 129X1/SvJ * C57BL/6
Reduction in the complexity of the peripheral ER in neurons in the primary motor cortex of Reep1tm1.1Cahb/Reep1tm1.1Cahb miceReep1tm1.1Cahb/Reep1tm1.1Cahbinvolves: 129S1/Sv * 129X1/SvJ * C57BL/6
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory