Phenotype Images associated with this Allele - MGI

About Help FAQ

Phenotype Images associated with this Allele

Nomenclature

Symbol:	Tgfb1^{tm1(Tgfb3)Kul}
Name:	transforming growth factor, beta 1; targeted mutation 1, Ashok B Kulkarni
MGI ID:	MGI:5559039
Synonyms:	TGF-beta1^Lbeta3

Images for
Allele

Click images for details

Image	Caption	Genotypes involving this allele
Image	Caption	Allelic Composition	Genetic Background
	Reduced size, kyphosis, tooth abnormalities, and decreased mineral density and dental attrition in Tgfb1^{tm1(Tgfb3)Kul}/Tgfb1^{tm1(Tgfb3)Kul} mice	Tgfb1^{tm1(Tgfb3)Kul}/Tgfb1^{tm1(Tgfb3)Kul}	involves: 129S1/Sv * 129X1/SvJ * C57BL/6
	Defects in secondary ossification in Tgfb1^{tm1(Tgfb3)Kul}/Tgfb1^{tm1(Tgfb3)Kul} mice	Tgfb1^{tm1(Tgfb3)Kul}/Tgfb1^{tm1(Tgfb3)Kul}	involves: 129S1/Sv * 129X1/SvJ * C57BL/6
	Tgfb1^{tm1(Tgfb3)Kul}/Tgfb1^{tm1(Tgfb3)Kul} mice remain small and thin on a high fat dough diet	Tgfb1^{tm1(Tgfb3)Kul}/Tgfb1^{tm1(Tgfb3)Kul}	involves: 129S1/Sv * 129X1/SvJ * C57BL/6
	Reduction in adipose tissue underlying the skin dermis, reduced adipocyte size and no development of steatosis in Tgfb1^{tm1(Tgfb3)Kul}/Tgfb1^{tm1(Tgfb3)Kul} mice fed a high fat dough diet	Tgfb1^{tm1(Tgfb3)Kul}/Tgfb1^{tm1(Tgfb3)Kul}	involves: 129S1/Sv * 129X1/SvJ * C57BL/6

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/12/2024 MGI 6.24