Phenotype Images associated with this Allele - MGI

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Phenotype Images associated with this Allele

Nomenclature

Symbol:	Adamts6^b2b2405Clo
Name:	ADAM metallopeptidase with thrombospondin type 1 motif 6; Bench to Bassinet Program (B2B/CVDC), mutation 2405 Cecilia Lo
MGI ID:	MGI:5560144

Images for
Allele

Click images for details

Image	Caption	Genotypes involving this allele
Image	Caption	Allelic Composition	Genetic Background
	Mutant 2405-003-2 (E15.5) exhibits abnormal placement of the great arteries which is diagnosed as DORV by EFIC imaging	Adamts6^b2b2405Clo/Adamts6^b2b2405Clo	C57BL/6J-Adamts6^b2b2405Clo
	EFIC Summary	Adamts6^b2b2405Clo/Adamts6^b2b2405Clo	C57BL/6J-Adamts6^b2b2405Clo
	Serial 2D EFIC image stack in the coronal plane of 2405-003-2 (E15.5) shows DORV and subaortic VSD Click thumbnail to play movie.	Adamts6^b2b2405Clo/Adamts6^b2b2405Clo	C57BL/6J-Adamts6^b2b2405Clo
	Mutant 2405-003-2 (E15.5) presents with abnormally attached hindlimbs and hydrops	Adamts6^b2b2405Clo/Adamts6^b2b2405Clo	C57BL/6J-Adamts6^b2b2405Clo
	Mutant 2405-003-2 (E15.5) has a hypoplastic thymus	Adamts6^b2b2405Clo/Adamts6^b2b2405Clo	C57BL/6J-Adamts6^b2b2405Clo
	Mutant 2405-003-6 (E15.5) presents with a short snout, abnormally attached hindlimbs, and hydrops	Adamts6^b2b2405Clo/Adamts6^b2b2405Clo	C57BL/6J-Adamts6^b2b2405Clo
	Mutant 2405-003-6 (E15.5) shows a hypoplastic thymus	Adamts6^b2b2405Clo/Adamts6^b2b2405Clo	C57BL/6J-Adamts6^b2b2405Clo
	Mutant 2405-003-6 (E15.5) presents with a hypoplastic transverse arch and biventricular hypertrophy which was also seen by EFIC imaging	Adamts6^b2b2405Clo/Adamts6^b2b2405Clo	C57BL/6J-Adamts6^b2b2405Clo
	EFIC Summary	Adamts6^b2b2405Clo/Adamts6^b2b2405Clo	C57BL/6J-Adamts6^b2b2405Clo
	Serial 2D EFIC image stack in the coronal plane of 2405-003-6 (E15.5) shows overriding aorta, AVSD, and biventricular hypertrophy Click thumbnail to play movie.	Adamts6^b2b2405Clo/Adamts6^b2b2405Clo	C57BL/6J-Adamts6^b2b2405Clo
	Mutant 2405-005-NA has abnormally attached hindlimbs, a short snout, and micrognathia	Adamts6^b2b2405Clo/Adamts6^b2b2405Clo	C57BL/6J-Adamts6^b2b2405Clo
	Mutant 2405-005-NA exhibits an unfused sternum	Adamts6^b2b2405Clo/Adamts6^b2b2405Clo	C57BL/6J-Adamts6^b2b2405Clo
	Mutant 2405-005-NA presents with a hypoplastic thymus	Adamts6^b2b2405Clo/Adamts6^b2b2405Clo	C57BL/6J-Adamts6^b2b2405Clo

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