Phenotype Images associated with this Allele
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Nomenclature
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Symbol:
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b2b2588Clo
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Name:
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Mutant line 2588;
Bench to Bassinet Program (B2B/CVDC), mutation 2588 Cecilia Lo
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MGI ID:
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MGI:5560906
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Synonyms:
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Kanga
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Images for
Allele
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Click images for details
 | Mutant 2588-003-2 (E16.5) presents with right aortic arch and parallel outflow tracts, shown to be DORV by EFIC imaging | b2b2588Clo/b2b2588Clo | C57BL/6J-b2b2588Clo |
 | EFIC Summary | b2b2588Clo/b2b2588Clo | C57BL/6J-b2b2588Clo |
 | Serial 2D EFIC image stack in the coronal plane of 2588-003-2 (E16.5) reveals DORV, subaortic VSD, RAA, aberrant left subclavian artery arising from PA, and biventricular hyperptrophy
Click thumbnail to play movie. | b2b2588Clo/b2b2588Clo | C57BL/6J-b2b2588Clo |
 | Color flow spectral Doppler imaging of mutant 2588-003 (E16.5) in the transverse view shows shunting between LV and RV, suggesting VSD
Click thumbnail to play movie. | b2b2588Clo/b2b2588Clo | C57BL/6J-b2b2588Clo |
 | Color flow spectral Doppler imaging of mutant 2588-003 (E16.5) in the sagittal view shows aorta overriding over septum, suggesting DORV | b2b2588Clo/b2b2588Clo | C57BL/6J-b2b2588Clo |
 | Mutant 2588-003-2 (E16.5) presents with gastroschisis | b2b2588Clo/b2b2588Clo | C57BL/6J-b2b2588Clo |
 | Mutant 2588-003-2 (E16.5) has cleft palate | b2b2588Clo/b2b2588Clo | C57BL/6J-b2b2588Clo |
 | Mutant 2588-003-2 (E16.5) has hypoplastic thymus | b2b2588Clo/b2b2588Clo | C57BL/6J-b2b2588Clo |
 | Mutant 2588-003-1 (E16.5) exhibits right aortic arch with parallel outflow tracts which was confirmed as DORV by EFIC imaging | b2b2588Clo/b2b2588Clo | C57BL/6J-b2b2588Clo |
 | EFIC Summary | b2b2588Clo/b2b2588Clo | C57BL/6J-b2b2588Clo |
 | Serial 2D EFIC image stack in the coronal plane of dead fetus 2588-003-1 (E16.5) reveals developmental arrest prior to E14.5 with DORV, AVSD, RAA, and cushion-like AV valve
Click thumbnail to play movie. | b2b2588Clo/b2b2588Clo | C57BL/6J-b2b2588Clo |
 | Mutant 2588-003-1 (E16.5) exhibits gastroschisis | b2b2588Clo/b2b2588Clo | C57BL/6J-b2b2588Clo |
 | Mutant 2588-003-1 (E16.5) has cleft palate | b2b2588Clo/b2b2588Clo | C57BL/6J-b2b2588Clo |
 | Mutant 2588-003-3 (E16.5) exhibits an abnormal arrangement of the great arteries, confirmed to be DORV by EFIC imaging | b2b2588Clo/b2b2588Clo | C57BL/6J-b2b2588Clo |
 | EFIC Summary | b2b2588Clo/b2b2588Clo | C57BL/6J-b2b2588Clo |
 | Serial 2D EFIC image stack in the coronal plane of 2588-003-3 (E16.5) shows DORV and subaortic VSD
Click thumbnail to play movie. | b2b2588Clo/b2b2588Clo | C57BL/6J-b2b2588Clo |
 | Mutant 2588-003-3 (E16.5) has cystic kidneys | b2b2588Clo/b2b2588Clo | C57BL/6J-b2b2588Clo |
 | Mutant 2588-003-3 (E16.5) has cystic kidneys | b2b2588Clo/b2b2588Clo | C57BL/6J-b2b2588Clo |
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