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Phenotype Images associated with this Allele
Nomenclature
Symbol: Evlb2b2600Clo
Name: Ena-vasodilator stimulated phosphoprotein; Bench to Bassinet Program (B2B/CVDC) mutation 2600, Cecilia Lo
MGI ID: MGI:5560907
Images for
Allele
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Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Mutant 2600-005-1 (E16.5) exhibits abnormal arrangement of the great arteries and thin ventricular walls which is diagnosed as DORV and ventricular non-compaction by EFIC imagingEvlb2b2600Clo/Evlb2b2600CloC57BL/6J-Evlb2b2600Clo
EFIC SummaryEvlb2b2600Clo/Evlb2b2600CloC57BL/6J-Evlb2b2600Clo
Serial 2D EFIC image stack in the coronal plane of mutant 2600-005-1 (E16.5) shows DORV, AVSD, mVSD, and ventricular myocardial non-compaction
Click thumbnail to play movie.		Evlb2b2600Clo/Evlb2b2600CloC57BL/6J-Evlb2b2600Clo
Mutant 2600-005-1 (E16.5) is runted, has hydrops, and open eyelidsEvlb2b2600Clo/Evlb2b2600CloC57BL/6J-Evlb2b2600Clo
Mutant 2600-005-1 (E16.5) exhibits a hypoplastic thymusEvlb2b2600Clo/Evlb2b2600CloC57BL/6J-Evlb2b2600Clo
EFIC SummaryEvlb2b2600Clo/Evlb2b2600CloC57BL/6J-Evlb2b2600Clo
Serial 2D EFIC image stack in the coronal plane of mutant 2600-003-NB shows AVSD and biventricular hypertrophy
Click thumbnail to play movie.		Evlb2b2600Clo/Evlb2b2600CloC57BL/6J-Evlb2b2600Clo
2600-003-NB exhibits short snout and micrognathiaEvlb2b2600Clo/Evlb2b2600CloC57BL/6J-Evlb2b2600Clo
Mutant 2600-003-NB presents with a slightly hypoplastic thymus and biventricular hypertrophy that is also seen by EFIC imagingEvlb2b2600Clo/Evlb2b2600CloC57BL/6J-Evlb2b2600Clo
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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10/29/2024
MGI 6.24 		The Jackson Laboratory