Phenotype Images associated with this Allele
Nomenclature
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Symbol:
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b2b2739Clo
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Name:
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Mutant line 2739;
Bench to Bassinet Program (B2B/CVDC), mutation 2739 Cecilia Lo
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MGI ID:
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MGI:5560910
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Images for Allele
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Click images for details
| Mutant 2739-005-1 (E15.5) shows abnormal arrangement of the great arteries and thin ventricular walls which is diagnosed as DORV and ventricular non-compaction by EFIC imaging | b2b2739Clo/b2b2739Clo | C57BL/6J-b2b2739Clo |
| EFIC Summary | b2b2739Clo/b2b2739Clo | C57BL/6J-b2b2739Clo |
| Serial 2D EFIC image stack of 2739-005-1 (E15.5) in the coronal section reveals DORV {S,D,D}, AVSD, ventricular non-compaction, cushion-like atrioventricular valve and semilunar valves Click thumbnail to play movie. | b2b2739Clo/b2b2739Clo | C57BL/6J-b2b2739Clo |
| Mutant 2739-005-1 (E15.5) is runted with patechiae, hydrops, anophthalmia, and craniofacial defects with micrognathia | b2b2739Clo/b2b2739Clo | C57BL/6J-b2b2739Clo |
| Mutant 2739-005-1 (E15.5) exhibits cleft lip and cleft palate associated with failure of the frontal nasal prominence to close | b2b2739Clo/b2b2739Clo | C57BL/6J-b2b2739Clo |
| Mutant 2739-005-3 (E15.5) exhibits parallel outflow tracts and RAA which is diagnosed as DORV by EFIC imaging | b2b2739Clo/b2b2739Clo | C57BL/6J-b2b2739Clo |
| EFIC Summary | b2b2739Clo/b2b2739Clo | C57BL/6J-b2b2739Clo |
| Serial 2D EFIC image stack of 2739-005-3 (E15.5) in the coronal plane reveals Taussig Bing type DORV {A,D,D}, AVSD, common atrium, RAA, aberrant left subclavian artery forming vascular ring, ventricular non-compaction, left lung isomerism, left hepatic vein and right IVC connect to atria Click thumbnail to play movie. | b2b2739Clo/b2b2739Clo | C57BL/6J-b2b2739Clo |
| Mutant 2739-005-3 (E15.5) is runted and pale. Mutant also exhibits hydrops, petechiae, and right micropthalmia | b2b2739Clo/b2b2739Clo | C57BL/6J-b2b2739Clo |
| Mutant 2739-005-3 (E15.5) presents with micropthalmia of right eye, and cleft lip | b2b2739Clo/b2b2739Clo | C57BL/6J-b2b2739Clo |
| Mutant 2739-005-3 (E15.5) shows a cleft palate | b2b2739Clo/b2b2739Clo | C57BL/6J-b2b2739Clo |
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