Phenotype Images associated with this Allele - MGI

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Phenotype Images associated with this Allele

Nomenclature

Symbol:	Cplane2^b2b2827Clo
Name:	ciliogenesis and planar polarity effector 2; Bench to Bassinet Program (B2B/CVDC), mutation 2827 Cecilia Lo
MGI ID:	MGI:5560911

Images for
Allele

Click images for details

Image	Caption	Genotypes involving this allele
Image	Caption	Allelic Composition	Genetic Background
	Mutant 2827-004-1 (E16.5) exhibits heterotaxy with dextrocardia, PTA, and hypoplastic lungs	Cplane2^b2b2827Clo/Cplane2^b2b2827Clo	C57BL/6J-Cplane2^b2b2827Clo
	EFIC Summary	Cplane2^b2b2827Clo/Cplane2^b2b2827Clo	C57BL/6J-Cplane2^b2b2827Clo
	Serial 2D EFIC stack of 2827-004-1 (E16.5) in the coronal plane reveals dextrocardia {A,A(D),A}, superior-inferior ventricles, juxtaposition of atria, AVSD, common atrium, RAA, pulmonary atresia, tracheoesophageal fistula, and no major pulmonary arteries identified Click thumbnail to play movie.	Cplane2^b2b2827Clo/Cplane2^b2b2827Clo	C57BL/6J-Cplane2^b2b2827Clo
	Mutant 2827-004-1 (E16.5) exhibits preaxial and central polydactyly on all limbs, microphthalmia, hydrops, and micrognathia	Cplane2^b2b2827Clo/Cplane2^b2b2827Clo	C57BL/6J-Cplane2^b2b2827Clo
	Mutant 2827-004-1 (E16.5) shows a cleft lip	Cplane2^b2b2827Clo/Cplane2^b2b2827Clo	C57BL/6J-Cplane2^b2b2827Clo
	Mutant 2827-004-1 (E16.5) shows a hypoplastic thymus	Cplane2^b2b2827Clo/Cplane2^b2b2827Clo	C57BL/6J-Cplane2^b2b2827Clo
	Mutant 2827-004-1 (E16.5) exhibits heterotaxy with dextrocardia and levogastria	Cplane2^b2b2827Clo/Cplane2^b2b2827Clo	C57BL/6J-Cplane2^b2b2827Clo
	Mutant 2827-004-2 (E16.5) has PTA and hypoplastic lungs as confirmed by EFIC imaging	Cplane2^b2b2827Clo/Cplane2^b2b2827Clo	C57BL/6J-Cplane2^b2b2827Clo
	EFIC Summary	Cplane2^b2b2827Clo/Cplane2^b2b2827Clo	C57BL/6J-Cplane2^b2b2827Clo
	Serial 2D EFIC image stack of 2827-004-2 (E16.5) in the coronal plane reveals PTA {A,D,D(A)}, AVSD, common atrium, hypoplastic lungs connected to esophagus, trachea not identified, right IVC and left hepatic vein connected to atrium Click thumbnail to play movie.	Cplane2^b2b2827Clo/Cplane2^b2b2827Clo	C57BL/6J-Cplane2^b2b2827Clo
	Mutant 2827-004-2 (E16.5) is runted, has preaxial and central polydactyly on all limbs, cleft lip, and anophthalmia	Cplane2^b2b2827Clo/Cplane2^b2b2827Clo	C57BL/6J-Cplane2^b2b2827Clo
	Mutant 2827-004-2 (E16.5) presents with anophthalmia, micrognathia, and hydrops	Cplane2^b2b2827Clo/Cplane2^b2b2827Clo	C57BL/6J-Cplane2^b2b2827Clo

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