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Phenotype Images associated with this Allele
Nomenclature
Symbol: Sel1ltm1c(KOMP)Wtsi
Name: sel-1 suppressor of lin-12-like (C. elegans); targeted mutation 1c, Welcome Trust Sanger Institute
MGI ID: MGI:5576558
Synonyms: Sel1Lf
Images for
Allele
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Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Exocrine pancreatic insufficiency in Sel1ltm1c(KOMP)Wtsi/Sel1ltm1c(KOMP)Wtsi Tg(CAG-cre/Esr1*)5Amc/0 miceSel1ltm1c(KOMP)Wtsi/Sel1ltm1c(KOMP)Wtsi
Tg(CAG-cre/Esr1*)5Amc/0
involves: C57BL/6 * C57BL/6N * CBA * SJL
Dilated endoplasmic reticulum and smaller zymogen granules in the exocrine pancreas of Sel1ltm1c(KOMP)Wtsi/Sel1ltm1c(KOMP)Wtsi Tg(CAG-cre/Esr1*)5Amc/0 miceSel1ltm1c(KOMP)Wtsi/Sel1ltm1c(KOMP)Wtsi
Tg(CAG-cre/Esr1*)5Amc/0
involves: C57BL/6 * C57BL/6N * CBA * SJL
Sel1ltm1c(KOMP)Wtsi/Sel1ltm1c(KOMP)Wtsi Tg(CAG-cre/Esr1*)5Amc/0 mice develop exocrine pancreatic insufficiency and nutrient malabsorptionSel1ltm1c(KOMP)Wtsi/Sel1ltm1c(KOMP)Wtsi
Tg(CAG-cre/Esr1*)5Amc/0
involves: C57BL/6 * C57BL/6N * CBA * SJL
Decreased cell proliferation in the exocrine pancreas in Sel1ltm1c(KOMP)Wtsi/Sel1ltm1c(KOMP)Wtsi Tg(CAG-cre/Esr1*)5Amc/0 miceSel1ltm1c(KOMP)Wtsi/Sel1ltm1c(KOMP)Wtsi
Tg(CAG-cre/Esr1*)5Amc/0
involves: C57BL/6 * C57BL/6N * CBA * SJL

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory