About   Help   FAQ
Phenotype Images associated with this Allele
Nomenclature
Symbol: Lrrc8atm1.1Geha
Name: leucine rich repeat containing 8A VRAC subunit A; targeted mutation 1.1, Raif S Geha
MGI ID: MGI:5581436
Synonyms: Lrrc8a-
Images for
Allele
Click images for details
Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Growth retardation, epidermal hyperkeratosis, thin skeletal muscle bundles, vacuolated renal tubular cells, and absence of ovarian corpora lutea in Lrrc8atm1.1Geha/Lrrc8atm1.1Geha miceLrrc8atm1.1Geha/Lrrc8atm1.1GehaB6.129S1(Cg)-Lrrc8atm1.1Geha
Lrrc8atm1.1Geha/Lrrc8atm1.1Geha mice have small spleens with well-preserved architectureLrrc8atm1.1Geha/Lrrc8atm1.1GehaB6.129S1(Cg)-Lrrc8atm1.1Geha
Decreased thymic cellularity and impaired thymocyte viability in Lrrc8atm1.1Geha/Lrrc8atm1.1Geha miceLrrc8atm1.1Geha/Lrrc8atm1.1GehaB6.129S1(Cg)-Lrrc8atm1.1Geha
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
10/09/2024
MGI 6.24 		The Jackson Laboratory