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Phenotype Images associated with this Allele
Nomenclature
Symbol: Lrrc8atm1.1Geha
Name: leucine rich repeat containing 8A VRAC subunit A; targeted mutation 1.1, Raif S Geha
MGI ID: MGI:5581436
Synonyms: Lrrc8a-
Images for
Allele
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Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Growth retardation, epidermal hyperkeratosis, thin skeletal muscle bundles, vacuolated renal tubular cells, and absence of ovarian corpora lutea in Lrrc8atm1.1Geha/Lrrc8atm1.1Geha miceLrrc8atm1.1Geha/Lrrc8atm1.1GehaB6.129S1(Cg)-Lrrc8atm1.1Geha
Lrrc8atm1.1Geha/Lrrc8atm1.1Geha mice have small spleens with well-preserved architectureLrrc8atm1.1Geha/Lrrc8atm1.1GehaB6.129S1(Cg)-Lrrc8atm1.1Geha
Decreased thymic cellularity and impaired thymocyte viability in Lrrc8atm1.1Geha/Lrrc8atm1.1Geha miceLrrc8atm1.1Geha/Lrrc8atm1.1GehaB6.129S1(Cg)-Lrrc8atm1.1Geha
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory