Phenotype Images associated with this Allele
Nomenclature
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Symbol:
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Amnb2b2259Clo
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Name:
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amnionless;
Bench to Bassinet Program (B2B/CVDC), mutation 2259 Cecilia Lo
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MGI ID:
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MGI:5614775
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Images for Allele
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Click images for details
| Mutant (E14.5) shows malpositioned outflow tracts with possible right aortic arch. | Amnb2b2259Clo/Amnb2b2259Clo | C57BL/6J-Amnb2b2259Clo |
| EFIC Summary | Amnb2b2259Clo/Amnb2b2259Clo | C57BL/6J-Amnb2b2259Clo |
| Serial 2D ECM image stack in the coronal plane of 2259-003-1 (E14.5) reveals double outlet right ventricle (DORV), subaortic VSD, right aortic arch, hypoplastic pulmonary artery, ventricular non-compaction, aberrant left subclavian artery forming incomplete vascular ring Click thumbnail to play movie. | Amnb2b2259Clo/Amnb2b2259Clo | C57BL/6J-Amnb2b2259Clo |
| Mutant (E14.5) presents with hydrops, left micropthalmia, and is runted | Amnb2b2259Clo/Amnb2b2259Clo | C57BL/6J-Amnb2b2259Clo |
| EFIC Summary | Amnb2b2259Clo/Amnb2b2259Clo | C57BL/6J-Amnb2b2259Clo |
| Serial 2D ECM image stack in the coronal plane of 2259-007-NA reveals double outlet right ventricle (DORV), subaortic ventricular septal defect (VSD), right aortic arch (RAA), hypoplastic pulmonary artery (PA), and biventricular hypertrophy. Click thumbnail to play movie. | Amnb2b2259Clo/Amnb2b2259Clo | C57BL/6J-Amnb2b2259Clo |
| Mutant exhibits malaligned sternal vertebrae. | Amnb2b2259Clo/Amnb2b2259Clo | C57BL/6J-Amnb2b2259Clo |
| Mutant exhibits parallel outflow tracts with right aortic arch, which was diagnosed as double outlet right ventricle (DORV) with hypoplastic pulmonary artery (PA) by ECM histopathology. | Amnb2b2259Clo/Amnb2b2259Clo | C57BL/6J-Amnb2b2259Clo |
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