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Phenotype Images associated with this Allele
Nomenclature
Symbol: Dnah5b2b2570Clo
Name: dynein, axonemal, heavy chain 5; Bench to Bassinet Program (B2B/CVDC), mutation 2570 Cecilia Lo
MGI ID: MGI:5614979
Images for
Allele
Click images for details
Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Mutant exhibits situs inversus totalis with dextrocardia and dextrogastria.Dnah5b2b2570Clo/Dnah5b2b2570CloC57BL/6J-Dnah5b2b2570Clo
Mutant shows mirror image dextrocardia with inverted positioning of the outflows.Dnah5b2b2570Clo/Dnah5b2b2570CloC57BL/6J-Dnah5b2b2570Clo
EFIC SummaryDnah5b2b2570Clo/Dnah5b2b2570CloC57BL/6J-Dnah5b2b2570Clo
Serial 2D ECM image stack in the coronal plane reveals mirror image dextrocardia.
Click thumbnail to play movie.		Dnah5b2b2570Clo/Dnah5b2b2570CloC57BL/6J-Dnah5b2b2570Clo
Mutant shows inverted positioning of the kidneys with right kidney lower then the left kidney.Dnah5b2b2570Clo/Dnah5b2b2570CloC57BL/6J-Dnah5b2b2570Clo
Mutant exhibits situs inversus totalis with dextrocardia and dextrogastria.Dnah5b2b2570Clo/Dnah5b2b2570CloC57BL/6J-Dnah5b2b2570Clo
Mutant exhibit immotile cilia in the tracheal airway epithelia.
Click thumbnail to play movie.		Dnah5b2b2570Clo/Dnah5b2b2570CloC57BL/6J-Dnah5b2b2570Clo
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
08/02/2024
MGI 6.24 		The Jackson Laboratory