Images for
Allele
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Click images for details
 | Mutant (E14.5) shows a malrotated heart which is diagnosed as superior-inferior ventricles by ECM histopathology. | | |
 | Mutant (E14.5) shows abnormal arrangement of the outflow tracts which was diagnosed by ECM histopathology as double outlet right ventricle (DORV) with interrupted aortic arch (type C) and a hypoplastic pulmonary artery. | | |
 | EFIC Summary | | |
 | Serial 2D ECM image stack in the coronal plane of mutant (E14.5) reveals {A(I),A,D}, superior-inferior ventricles, double outlet right ventricle (DORV), atrioventricular septal defect (AVSD), common atrium, interrupted aortic arch (type C), hypoplastic pulmonary artery (PA), aberrant right subclavian artery forming incomplete vascular ring. Single lung lobe, left sided inferior vena cava (IVC), total anomalous pulmonary venous return (TAPVR), and left lung isomerism.
Click thumbnail to play movie. | | |
 | Mutant (E14.5) shows dextrogastria and asplenia. | | |
 | Mutant (E14.5) exhibits hydrops and petechiae as well as severe craniofacial defects including microcephaly, proboscis, agnathia, and cyclopia | | |
 | EFIC Summary | | |
 | Serial 2D ECM image stack of (ED14.5) in the coronal plane revelas atrioventricular septal defect (AVSD), small LV, thick cushion like atrioventricular (AV) valve.
Click thumbnail to play movie. | | |
 | Mutant (E14.5) exhibits hydrops and petechiae as well as severe craniofacial defects including hydrops, petechiae, microcephaly, proboscis, and agnathia | | |
 | Mutant (E14.5) has severe craniofacial defects consistent with otocephaly which include microcephaly with cyclopia, proboscis, and agnathia | | |
 | Mutant (E14.5) exhibits a hypoplastic thymus and a left-sided inferior vena cava (IVC). | | |
 | Mutant (E14.5) exhibits severe craniofacial defects including agnathia with proboscis, anencephaly, anopthalmia, low-set ears. | | |
 | Mutant (E14.5) exhibits craniofacial defects including bilateral anopthalmia, short, narrow snout, agnathia, astomia, and low-set ears | | |
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