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Phenotype Images associated with this Allele
Nomenclature
Symbol: b2b2696.1Clo
Name: Mutant line 2696.1; Bench to Bassinet Program (B2B/CVDC), mutation 2696, subline 1 Cecilia Lo
MGI ID: MGI:5620186
Images for
Allele
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Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Mutant (E14.5) shows dextrocardia with abnormal outflow tract arrangement with DORV as seen by ECM hisopathology.b2b2696Clo/b2b2696CloC57BL/6J-b2b2696Clo
b2b2696.1Clo/b2b2696.1CloC57BL/6J-b2b2696.1Clo
EFIC Summaryb2b2696Clo/b2b2696CloC57BL/6J-b2b2696Clo
b2b2696.1Clo/b2b2696.1CloC57BL/6J-b2b2696.1Clo
Serial 2D ECM image stack of (ED14.5) in the coronal plane reveals dextracardia {A,D,D} with DORV, AVSD, muscular VSD, right atrial isomerism with absent coronary sinus, intracardiac TAPVR, dual IVC, left aortic arch, delayed myocardial compaction (or myocardial non-compaction), and left lung isomerism.
Click thumbnail to play movie.
b2b2696Clo/b2b2696CloC57BL/6J-b2b2696Clo
b2b2696.1Clo/b2b2696.1CloC57BL/6J-b2b2696.1Clo
Mutant (E14.5) presents with a right-sided pancreas, asplenia, left-sided stomach and gut malrotation.b2b2696Clo/b2b2696CloC57BL/6J-b2b2696Clo
b2b2696.1Clo/b2b2696.1CloC57BL/6J-b2b2696.1Clo

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory