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Phenotype Images associated with this Allele
Nomenclature
Symbol: b2b2696.2Clo
Name: Mutant line 2696.2; Bench to Bassinet Program (B2B/CVDC), mutation 2696, subline 2 Cecilia Lo
MGI ID: MGI:5620188
Images for
Allele
Click images for details
Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Mutant exhibits a right aortic arch which was confirmed by ECM imaging.b2b2696Clo/b2b2696CloC57BL/6J-b2b2696Clo
b2b2696.2Clo/b2b2696.2CloC57BL/6J-b2b2696.2Clo
EFIC Summaryb2b2696Clo/b2b2696CloC57BL/6J-b2b2696Clo
b2b2696.2Clo/b2b2696.2CloC57BL/6J-b2b2696.2Clo
Serial 2D ECM image stack in the coronal plane of mutant reveals right aortic arch, coronary artery fistula, and aberrant left subclavian artery forming incomplete vascular ring.
Click thumbnail to play movie.		b2b2696Clo/b2b2696CloC57BL/6J-b2b2696Clo
b2b2696.2Clo/b2b2696.2CloC57BL/6J-b2b2696.2Clo
Mutant exhibits craniofacial defects which include craniofacial hypoplasia, severe micrognathia/agnathia, bilateral anopthalmia, and low-set ears.b2b2696Clo/b2b2696CloC57BL/6J-b2b2696Clo
b2b2696.2Clo/b2b2696.2CloC57BL/6J-b2b2696.2Clo
Mutant presents with apparent left ventricular hypertrophy which was confirmed by ECM histopathologb2b2696Clo/b2b2696CloC57BL/6J-b2b2696Clo
b2b2696.2Clo/b2b2696.2CloC57BL/6J-b2b2696.2Clo
EFIC Summaryb2b2696Clo/b2b2696CloC57BL/6J-b2b2696Clo
b2b2696.2Clo/b2b2696.2CloC57BL/6J-b2b2696.2Clo
Serial 2D ECM image stack in the coronal plane of mutant reveals atrioventricular septal defect (AVSD) with apparent left ventricular hypertrophy.
Click thumbnail to play movie.		b2b2696Clo/b2b2696CloC57BL/6J-b2b2696Clo
b2b2696.2Clo/b2b2696.2CloC57BL/6J-b2b2696.2Clo
Mutant presents with right sided anopthalmia.b2b2696Clo/b2b2696CloC57BL/6J-b2b2696Clo
b2b2696.2Clo/b2b2696.2CloC57BL/6J-b2b2696.2Clo
Mutant exhibits cryptophthalmos, short snout, micrognathia, and low-set ears.b2b2696Clo/b2b2696CloC57BL/6J-b2b2696Clo
b2b2696.2Clo/b2b2696.2CloC57BL/6J-b2b2696.2Clo
Mutant presents with unilateral anopathalmia and left sided cryptophthalmos.b2b2696Clo/b2b2696CloC57BL/6J-b2b2696Clo
b2b2696.2Clo/b2b2696.2CloC57BL/6J-b2b2696.2Clo
Mutant presents with a midline facial cleft.b2b2696Clo/b2b2696CloC57BL/6J-b2b2696Clo
b2b2696.2Clo/b2b2696.2CloC57BL/6J-b2b2696.2Clo
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory