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Phenotype Images associated with this Allele
Nomenclature
Symbol: Crxtm2.1Smgc
Name: cone-rod homeobox; targeted mutation 2.1, Shiming Chen
MGI ID: MGI:5621025
Synonyms: CrxR90W
Images for
Allele
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Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Crxtm1.1Smgc/Crxtm1.1Smgc, Crxtm2.1Smgc/Crxtm2.1Smgc, and Crxtm1Clc/Crxtm1Clc mice develop Leber Congenital Amaurosis-like retinopathyCrxtm1Clc/Crxtm1Clcinvolves: 129S6/SvEvTac
Crxtm1.1Smgc/Crxtm1.1SmgcB6.129X1(CBA)-Crxtm1.1Smgc
Crxtm2.1Smgc/Crxtm2.1SmgcB6.129X1(CBA)-Crxtm2.1Smgc
Crxtm1.1Smgc/Crx+ but not Crxtm2.1Smgc/Crx+ develop dominant retinopathyCrxtm1.1Smgc/Crx+B6.129X1(CBA)-Crxtm1.1Smgc
Crxtm2.1Smgc/Crx+B6.129X1(CBA)-Crxtm2.1Smgc
Crxtm1.1Smgc/Crx+, Crxtm1Smgc/Crx+ and Crxtm2.1Smgc/Crx+ mice display abnormal cone nuclear localization in developing and adult retinaCrxtm1.1Smgc/Crx+B6.129X1(CBA)-Crxtm1.1Smgc
Crxtm1Smgc/Crx+involves: 129X1/SvJ
Crxtm2.1Smgc/Crx+B6.129X1(CBA)-Crxtm2.1Smgc
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory