About   Help   FAQ
Phenotype Images associated with this Allele
Nomenclature
Symbol: Crxtm2.1Smgc
Name: cone-rod homeobox; targeted mutation 2.1, Shiming Chen
MGI ID: MGI:5621025
Synonyms: CrxR90W
Images for
Allele
Click images for details
Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Crxtm1.1Smgc/Crxtm1.1Smgc, Crxtm2.1Smgc/Crxtm2.1Smgc, and Crxtm1Clc/Crxtm1Clc mice develop Leber Congenital Amaurosis-like retinopathyCrxtm1Clc/Crxtm1Clcinvolves: 129S6/SvEvTac
Crxtm1.1Smgc/Crxtm1.1SmgcB6.129X1(CBA)-Crxtm1.1Smgc
Crxtm2.1Smgc/Crxtm2.1SmgcB6.129X1(CBA)-Crxtm2.1Smgc
Crxtm1.1Smgc/Crx+ but not Crxtm2.1Smgc/Crx+ develop dominant retinopathyCrxtm1.1Smgc/Crx+B6.129X1(CBA)-Crxtm1.1Smgc
Crxtm2.1Smgc/Crx+B6.129X1(CBA)-Crxtm2.1Smgc
Crxtm1.1Smgc/Crx+, Crxtm1Smgc/Crx+ and Crxtm2.1Smgc/Crx+ mice display abnormal cone nuclear localization in developing and adult retinaCrxtm1.1Smgc/Crx+B6.129X1(CBA)-Crxtm1.1Smgc
Crxtm1Smgc/Crx+involves: 129X1/SvJ
Crxtm2.1Smgc/Crx+B6.129X1(CBA)-Crxtm2.1Smgc
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory