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Phenotype Images associated with this Allele
Nomenclature
Symbol: Fitm2tm1.1Dls
Name: fat storage-inducing transmembrane protein 2; targeted mutation 1.1, David L Silver
MGI ID: MGI:5621176
Images for
Allele
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Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Reduced amounts of subcutaneous white adipose tissue and epididmyal white adipose tissue in Fitm2tm1.1Dls/Fitm2tm1.1Dls Tg(Fabp4-cre)1Rev/? miceFitm2tm1.1Dls/Fitm2tm1.1Dls
Tg(Fabp4-cre)1Rev/?
involves: 129S6/SvEvTac * C57BL/6J
Adipose tissue macrophage infiltration in Fitm2tm1.1DlsFitm2tm1.1Dls Tg(Fabp4-cre)1Rev/? miceFitm2tm1.1Dls/Fitm2tm1.1Dls
Tg(Fabp4-cre)1Rev/?
involves: 129S6/SvEvTac * C57BL/6J
Fitm2tm1.1Dls/Fitm2tm1.1Dls Tg(Fabp4-cre)1Rev/? (AF2KO) mice have reduced accumulation of adipose tissue in response to high fat dietFitm2tm1.1Dls/Fitm2tm1.1Dls
Tg(Fabp4-cre)1Rev/?
involves: 129S6/SvEvTac * C57BL/6J
Reduced adiposity and unilocular lipid droplets in Fitm2tm1.1Dls/Fitm2tm1.1Dls Tg(Fabp4-cre)1Rev/? Lepob/Lepob miceFitm2tm1.1Dls/Fitm2tm1.1Dls
Lepob/Lepob
Tg(Fabp4-cre)1Rev/?
involves: 129S6/SvEvTac * C57BL/6J
Increase in size of large lipid droplets in Fitm2tm1.1Dls/Fitm2tm1.1Dls Tg(Fabp4-cre)1Rev/? brown adipose tissueFitm2tm1.1Dls/Fitm2tm1.1Dls
Tg(Fabp4-cre)1Rev/?
involves: 129S6/SvEvTac * C57BL/6J

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/29/2024
MGI 6.24
The Jackson Laboratory