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Phenotype Images associated with this Allele
Nomenclature
Symbol: Arhgef28tm1.1Ddsr
Name: Rho guanine nucleotide exchange factor 28; targeted mutation 1.1, David D Schlaepfer
MGI ID: MGI:5638671
Images for
Allele
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Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Reduced size of Arhgef28tm1.1Ddsr/Arhgef28tm1.1Ddsr mice at 4 weeksArhgef28tm1.1Ddsr/Arhgef28tm1.1Ddsrinvolves: 129S6/SvEvTac * C57BL/6 * C57BL/6NTac * BALB/cJ
Movement of Arhgef28tm1.1Ddsr/Arhgef28tm1.1Ddsr MEFs is inhibited in the scratch wound migration assayArhgef28tm1.1Ddsr/Arhgef28tm1.1Ddsrinvolves: 129S6/SvEvTac * C57BL/6 * C57BL/6NTac * BALB/cJ
Decreased focal adhesions number in Arhgef28tm1.1Ddsr/Arhgef28tm1.1Ddsr mouse embryo fibroblasts on fibronectin at 90 minArhgef28tm1.1Ddsr/Arhgef28tm1.1Ddsrinvolves: 129S6/SvEvTac * C57BL/6 * C57BL/6NTac * BALB/cJ
Decreased focal adhesions number and size in Arhgef28tm1.1Ddsr/Arhgef28tm1.1Ddsr mouse embryo fibroblasts on fibronectin at 120 minArhgef28tm1.1Ddsr/Arhgef28tm1.1Ddsrinvolves: 129S6/SvEvTac * C57BL/6 * C57BL/6NTac * BALB/cJ
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory