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Phenotype Images associated with this Allele
Nomenclature
Symbol: Zfp366b2b2834Clo
Name: zinc finger protein 366; Bench to Bassinet Program (B2B/CVDC), mutation 2834 Cecilia Lo
MGI ID: MGI:5645262
Images for
Allele
Click images for details
Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Mutant 2834-003-3 (E14.5) presents with parallel great arteries, which is diagnosed as an overriding aorta by episcopic confocal histopathologyZfp366b2b2834Clo/Zfp366b2b2834CloC57BL/6J-Zfp366b2b2834Clo
EFIC SummaryZfp366b2b2834Clo/Zfp366b2b2834CloC57BL/6J-Zfp366b2b2834Clo
Serial 2D episcopic confocal microscopy image stack in the coronal plane of 2834-003-3 (E14.5) shows overriding aorta and pmVSD
Click thumbnail to play movie.		Zfp366b2b2834Clo/Zfp366b2b2834CloC57BL/6J-Zfp366b2b2834Clo
Color flow spectral Doppler imaging of mutant 2834-003-3 (E14.5) in the sagittal view shows Ao riding over the interventricular septum, suggesting overriding Ao
Click thumbnail to play movie.		Zfp366b2b2834Clo/Zfp366b2b2834CloC57BL/6J-Zfp366b2b2834Clo
Mutant 2834-003-3 (E14.5) exhibits micrognathia and hydrops.Zfp366b2b2834Clo/Zfp366b2b2834CloC57BL/6J-Zfp366b2b2834Clo
Mutant 2834-003-3 (E14.5) presents with a hypoplastic thymus.Zfp366b2b2834Clo/Zfp366b2b2834CloC57BL/6J-Zfp366b2b2834Clo
Mutant 2834-003-3 (E14.5) exhibits hydronephrosis.Zfp366b2b2834Clo/Zfp366b2b2834CloC57BL/6J-Zfp366b2b2834Clo
Mutant 2834-003-2 (E14.5) exhibits a hypoplastic thymus.Zfp366b2b2834Clo/Zfp366b2b2834CloC57BL/6J-Zfp366b2b2834Clo
Mutant 2834-003-1 (E14.5) shows a hypoplastic thymus.Zfp366b2b2834Clo/Zfp366b2b2834CloC57BL/6J-Zfp366b2b2834Clo
EFIC SummaryZfp366b2b2834Clo/Zfp366b2b2834CloC57BL/6J-Zfp366b2b2834Clo
Serial 2D episcopic confocal microscopy image stack in the coronal plane of 2834-003-2 (E14.5) shows a perimembranous VSD (pmVSD).
Click thumbnail to play movie.		Zfp366b2b2834Clo/Zfp366b2b2834CloC57BL/6J-Zfp366b2b2834Clo
Mutant 2834-003-2 (E14.5) shows micrognathia and hydrops.Zfp366b2b2834Clo/Zfp366b2b2834CloC57BL/6J-Zfp366b2b2834Clo
Mutant 2834-003-2 (E14.5) presents with hydronephrosis.Zfp366b2b2834Clo/Zfp366b2b2834CloC57BL/6J-Zfp366b2b2834Clo
EFIC SummaryZfp366b2b2834Clo/Zfp366b2b2834CloC57BL/6J-Zfp366b2b2834Clo
Serial 2D episcopic confocal microscopy image stack in the coronal plane of 2834-003-1 (E14.5) shows a muscular VSD (mVSD).
Click thumbnail to play movie.		Zfp366b2b2834Clo/Zfp366b2b2834CloC57BL/6J-Zfp366b2b2834Clo
Mutant 2834-003-1 (E14.5) exhibits micrognathia and syndactyly on the left hindlimb.Zfp366b2b2834Clo/Zfp366b2b2834CloC57BL/6J-Zfp366b2b2834Clo
Mutant 2834-003-1 (E14.5) exhibits micropthalmia of the right eye and hydrops.Zfp366b2b2834Clo/Zfp366b2b2834CloC57BL/6J-Zfp366b2b2834Clo
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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12/17/2024
MGI 6.24 		The Jackson Laboratory