Phenotype Images associated with this Allele - MGI

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Phenotype Images associated with this Allele

Nomenclature

Symbol:	Plxnd1^b2b3150Clo
Name:	plexin D1; Bench to Bassinet Program (B2B/CVDC), mutation 3150 Cecilia Lo
MGI ID:	MGI:5648017

Images for
Allele

Click images for details

Image	Caption	Genotypes involving this allele
Image	Caption	Allelic Composition	Genetic Background
	Mutant 3150-003-2 (E15.5) exhibits a hypoplastic and malpositioned.	Plxnd1^b2b3150Clo/Plxnd1^b2b3150Clo	C57BL/6J-Plxnd1^b2b3150Clo
	Mutant 3150-003-2 (E15.5) presents with only one outflow tract which is diagnosed as PTA (Type 2) by EFIC imaging.	Plxnd1^b2b3150Clo/Plxnd1^b2b3150Clo	C57BL/6J-Plxnd1^b2b3150Clo
	EFIC Summary	Plxnd1^b2b3150Clo/Plxnd1^b2b3150Clo	C57BL/6J-Plxnd1^b2b3150Clo
	Serial 2D EFIC image stack in the coronal plane of mutant 3150-003-2 (E15.5) reveals PTA (Type 2), AVSD, RAA, and aberrant left subclavian artery forming incomplete vascular ring. Click thumbnail to play movie.	Plxnd1^b2b3150Clo/Plxnd1^b2b3150Clo	C57BL/6J-Plxnd1^b2b3150Clo
	Mutant 3150-003-2 (E15.5) exhibits right kidney agenesis and a hypoplastic left kidney.	Plxnd1^b2b3150Clo/Plxnd1^b2b3150Clo	C57BL/6J-Plxnd1^b2b3150Clo
	Mutant 3150-003-1 (E15.5) exhibits only one outflow tract which is diagnosed as PTA (type 2) by EFIC imaging.	Plxnd1^b2b3150Clo/Plxnd1^b2b3150Clo	C57BL/6J-Plxnd1^b2b3150Clo
	EFIC Summary	Plxnd1^b2b3150Clo/Plxnd1^b2b3150Clo	C57BL/6J-Plxnd1^b2b3150Clo
	Serial 2D EFIC image stack in the coronal plane of mutant 3150-003-1 (E15.5) reveals PTA (Type 2), AVSD, RAA, common atrium, mVSD, and aberrant left subclavian artery forming incomplete vascular ring. Click thumbnail to play movie.	Plxnd1^b2b3150Clo/Plxnd1^b2b3150Clo	C57BL/6J-Plxnd1^b2b3150Clo
	Mutant 3150-003-1 (E15.5) has micrognathia, a short snout, petechiae, and hydrops	Plxnd1^b2b3150Clo/Plxnd1^b2b3150Clo	C57BL/6J-Plxnd1^b2b3150Clo
	Mutant 3150-003-1 (E15.5) exhibits a cleft palate.	Plxnd1^b2b3150Clo/Plxnd1^b2b3150Clo	C57BL/6J-Plxnd1^b2b3150Clo
	Mutant 3150-003-1 (E15.5) presents with bilateral kidney agenesis.	Plxnd1^b2b3150Clo/Plxnd1^b2b3150Clo	C57BL/6J-Plxnd1^b2b3150Clo

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