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Phenotype Images associated with this Allele
Nomenclature
Symbol: Aldh2tm1.1Mak
Name: aldehyde dehydrogenase 2, mitochondrial; targeted mutation 1.1, Tak Mak
MGI ID: MGI:5701667
Synonyms: Aldh2E487K
Images for
Allele
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Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Increased sensitivity of heterozygous and homozgyous Aldh2tm1.1Mak mice to damage induced by chronic ethanol challengeAldh2tm1.1Mak/Aldh2+involves: 129S6/SvEvTac * C57BL/6J
Aldh2tm1.1Mak/Aldh2tm1.1Makinvolves: 129S6/SvEvTac * C57BL/6J
Accelerated liver tumor development in diethylnitrosamine-induced heterozygous and homozygous Aldh2tm1.1Mak miceAldh2tm1.1Mak/Aldh2+involves: 129S6/SvEvTac * C57BL/6J
Aldh2tm1.1Mak/Aldh2tm1.1Makinvolves: 129S6/SvEvTac * C57BL/6J
Skin hyperpigmentation in heterozgyous and homozgyous Aldh2tm1.1Mak mice receiving chronic ethanol feedingAldh2tm1.1Mak/Aldh2+involves: 129S6/SvEvTac * C57BL/6J
Aldh2tm1.1Mak/Aldh2tm1.1Makinvolves: 129S6/SvEvTac * C57BL/6J
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/17/2024
MGI 6.24 		The Jackson Laboratory