Phenotype Images associated with this Allele - MGI

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Phenotype Images associated with this Allele

Nomenclature

Symbol:	Ireb2^tm1.1Eal
Name:	iron responsive element binding protein 2; targeted mutation 1.1, Elizabeth A Leibold
MGI ID:	MGI:5702744
Synonyms:	Irp2^-

Images for
Allele

Click images for details

Image	Caption	Genotypes involving this allele
Image	Caption	Allelic Composition	Genetic Background
	Iron accumulates in specific brain regions of Ireb2^tm1.1Eal/Ireb2^tm1.1Eal mice	Ireb2^tm1.1Eal/Ireb2^tm1.1Eal	B6J.129-Ireb2^tm1.1Eal
	Iron accumulates in axons and oliogodendrocyte cell bodies of Ireb2^tm1.1Eal/Ireb2^tm1.1Eal mice	Ireb2^tm1.1Eal/Ireb2^tm1.1Eal	B6J.129-Ireb2^tm1.1Eal
	Iron is reduced in Purkinje neurons and in CA1 pyramidal neurons of Ireb2^tm1.1Eal/Ireb2^tm1.1Eal mice	Ireb2^tm1.1Eal/Ireb2^tm1.1Eal	B6J.129-Ireb2^tm1.1Eal
	Ferritin expression is increased in Ireb2^tm1.1Eal/Ireb2^tm1.1Eal neurons	Ireb2^tm1.1Eal/Ireb2^tm1.1Eal	B6J.129-Ireb2^tm1.1Eal
	Presence of Protoporphyrin IX-containing granules in the common bile duct of Ireb2^tm1.1Eal/Ireb2^tm1.1Eal mice	Ireb2^tm1.1Eal/Ireb2^tm1.1Eal	B6J.129-Ireb2^tm1.1Eal
	Iron accumulation in hippocampus and cerebellum of aged Ireb2^tm1.1Eal/Ireb2^tm1.1Eal mice	Ireb2^tm1.1Eal/Ireb2^tm1.1Eal	B6J.129-Ireb2^tm1.1Eal

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