Phenotype Images associated with this Allele - MGI

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Phenotype Images associated with this Allele

Nomenclature

Symbol:	Mtor^tm1.1Gcon
Name:	mechanistic target of rapamycin kinase; targeted mutation 1.1, Gianluigi Condorelli
MGI ID:	MGI:5707218
Synonyms:	Mtor^fl

Images for
Allele

Click images for details

Image	Caption	Genotypes involving this allele
Image	Caption	Allelic Composition	Genetic Background
	Enlarged hearts with thinned ventricular walls and enlarged cardiac chambers in Mtor^tm1.1Gcon/Mtor^tm1.1Gcon A1cf^{Tg(Myh6-cre/Esr1*)1Jmk}/0 mice	Mtor^tm1.1Gcon/Mtor^tm1.1Gcon A1cf^{Tg(Myh6-cre/Esr1*)1Jmk}/A1cf⁺	involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB/N
	Left ventricle Mtor^tm1.1Gcon/Mtor^tm1.1Gcon A1cf^{Tg(Myh6-cre/Esr1*)1Jmk}/0 myocardium presents with sarcomeric disarray and swollen mitochondria and contains autophagic bodies after tamoxifen treatment	Mtor^tm1.1Gcon/Mtor^tm1.1Gcon A1cf^{Tg(Myh6-cre/Esr1*)1Jmk}/A1cf⁺	involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB/N

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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