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Phenotype Images associated with this Allele
Nomenclature
Symbol: Zfyve26tm1.1Cahb
Name: zinc finger, FYVE domain containing 26; targeted mutation 1.1, Christian A Hubner
MGI ID: MGI:5707975
Images for
Allele
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Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Abnormal gait of a Zfyve26tm1.1Cahb/Zfyve26tm1.1Cahb mouse walking on a beamZfyve26tm1.1Cahb/Zfyve26tm1.1Cahbinvolves: 129S1/Sv * 129X1/SvJ * BALB/cJ * C57BL/6
Severe neuron loss in the motor cortex and cerebellum of Zfyve26tm1.1Cahb/Zfyve26tm1.1Cahb miceZfyve26tm1.1Cahb/Zfyve26tm1.1Cahbinvolves: 129S1/Sv * 129X1/SvJ * BALB/cJ * C57BL/6
Accumulation of autofluorescent, electron-dense, membrane-enclosed material in Zfyve26tm1.1Cahb/Zfyve26tm1.1Cahb neuronsZfyve26tm1.1Cahb/Zfyve26tm1.1Cahbinvolves: 129S1/Sv * 129X1/SvJ * BALB/cJ * C57BL/6
Large autofluorescent particles in Zfyve26tm1.1Cahb/Zfyve26tm1.1Cahb mice localize to endolysosomesZfyve26tm1.1Cahb/Zfyve26tm1.1Cahbinvolves: 129S1/Sv * 129X1/SvJ * BALB/cJ * C57BL/6
Degenerating axons in the lumbar corticospinal tract of 8 month old Zfyve26tm1.1Cahb/Zfyve26tm1.1Cahb miceZfyve26tm1.1Cahb/Zfyve26tm1.1Cahbinvolves: 129S1/Sv * 129X1/SvJ * BALB/cJ * C57BL/6
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory