Phenotype Images associated with this Allele - MGI

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Phenotype Images associated with this Allele

Nomenclature

Symbol:	Tjp1^tm1.1Whun
Name:	tight junction protein 1; targeted mutation 1.1, Walter Hunziker
MGI ID:	MGI:5749399
Synonyms:	Tjp1^flox

Images for
Allele

Click images for details

Image	Caption	Genotypes involving this allele
Image	Caption	Allelic Composition	Genetic Background
	Growth retardation and severe glomerulosclerosis in Tjp1^tm1.1Whun/Tjp1^tm1.1WhunTg(Nphs1-cre)33Mska/0 mice	Tjp1^tm1.1Whun/Tjp1^tm1.1Whun Tg(Nphs1-cre)33Mska/0	involves: C57BL/6 * C57BL/6N * DBA/2
	Compromised foot process interdigitation and aberrant distribution of the slit diaphragm components in Tjp1^tm1.1Whun/Tjp1^tm1.1Whun Tg(Nphs1-cre)33Mska/0 mice	Tjp1^tm1.1Whun/Tjp1^tm1.1Whun Tg(Nphs1-cre)33Mska/0	involves: C57BL/6 * C57BL/6N * DBA/2
	Slit diaphragms are absent in the maturing stage of Tjp1^tm1.1Whun/Tjp1^tm1.1WhunTg(Nphs1-cre)33Mska/0 podocytes	Tjp1^tm1.1Whun/Tjp1^tm1.1Whun Tg(Nphs1-cre)33Mska/0	involves: C57BL/6 * C57BL/6N * DBA/2
	Defects in the glomerulus, dilated renal tubules, global foot process effacement and absent slit diaphragm in Tjp1^tm1.1Whun/Tjp1^tm1.1Whun Tg(Nphs1-cre)33Mska/0 mice	Tjp1^tm1.1Whun/Tjp1^tm1.1Whun Tg(Nphs1-cre)33Mska/0	involves: C57BL/6 * C57BL/6N * DBA/2

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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