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Phenotype Images associated with this Allele
Nomenclature
Symbol: Cep120tm1.1Blnw
Name: centrosomal protein 120; targeted mutation 1.1, Baolin Wang
MGI ID: MGI:5749512
Synonyms: Cep120f
Images for
Allele
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Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Hydrocephalus, dilated brain ventricles, and smaller cerebellum in Cep120tm1.1Blnw/Cep120tm1.2BlnwTg(Nes-cre)1Atp/0 miceCep120tm1.1Blnw/Cep120tm1.2Blnw
Tg(Nes-cre)1Atp/0
involves: 129S6/SvEvTac * C57BL/6 * FVB/N
Cerebellar hypoplasia in Cep120tm1.1Blnw/Cep120tm1.2BlnwTg(Nes-cre)1Atp/0 miceCep120tm1.1Blnw/Cep120tm1.2Blnw
Tg(Nes-cre)1Atp/0
involves: 129S6/SvEvTac * C57BL/6 * FVB/N
Failed expansion of granule neuron progenitors in Cep120tm1.1Blnw/Cep120tm1.2BlnwTg(Nes-cre)1Atp/0 miceCep120tm1.1Blnw/Cep120tm1.2Blnw
Tg(Nes-cre)1Atp/0
involves: 129S6/SvEvTac * C57BL/6 * FVB/N
Failed proliferation of granule neuron progenitors in Cep120tm1.1Blnw/Cep120tm1.2BlnwTg(Nes-cre)1Atp/0 cerebellumCep120tm1.1Blnw/Cep120tm1.2Blnw
Tg(Nes-cre)1Atp/0
involves: 129S6/SvEvTac * C57BL/6 * FVB/N
Failed centriole duplication, maturation, and ciliogenesis in cerebellar granule neuron progenitors and ependymal cells of Cep120tm1.1Blnw/Cep120tm1.2Blnw Tg(Nes-cre)1Atp/0 miceCep120tm1.1Blnw/Cep120tm1.2Blnw
Tg(Nes-cre)1Atp/0
involves: 129S6/SvEvTac * C57BL/6 * FVB/N

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory