About   Help   FAQ
Phenotype Images associated with this Allele
Nomenclature
Symbol: Srrm4tm1b(EUCOMM)Wtsi
Name: serine/arginine repetitive matrix 4; targeted mutation 1b, Wellcome Trust Sanger Institute
MGI ID: MGI:5752029
Synonyms: nSR100delta7-8
Images for
Allele
Click images for details
Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Impaired neurite outgrowth of Srrm4tm1b(EUCOMM)Wtsi/Srrm4tm1b(EUCOMM)Wtsi motor neuronsSrrm4tm1b(EUCOMM)Wtsi/Srrm4tm1b(EUCOMM)Wtsiinvolves: C57BL/6J * C57BL/6N
Srrm4tm1b(EUCOMM)Wtsi/Srrm4tm1b(EUCOMM)Wtsi mice display aberrant cortical layering and premature neurogenesisSrrm4tm1b(EUCOMM)Wtsi/Srrm4tm1b(EUCOMM)Wtsiinvolves: C57BL/6J * C57BL/6N
Midline crossing defects in Srrm4tm1b(EUCOMM)Wtsi/Srrm4tm1b(EUCOMM)Wtsi miceSrrm4tm1b(EUCOMM)Wtsi/Srrm4tm1b(EUCOMM)Wtsiinvolves: C57BL/6J * C57BL/6N
Primary hippocampal neurons from Srrm4tm1b(EUCOMM)Wtsi/Srrm4tm1b(EUCOMM)Wtsi mice show reduced neurite lengthSrrm4tm1b(EUCOMM)Wtsi/Srrm4tm1b(EUCOMM)Wtsiinvolves: C57BL/6J * C57BL/6N
Defective sprouting of secondary neurites but not the formation of neuromuscular junctions in Srrm4tm1b(EUCOMM)Wtsi/Srrm4tm1b(EUCOMM)Wtsi miceSrrm4tm1b(EUCOMM)Wtsi/Srrm4tm1b(EUCOMM)Wtsiinvolves: C57BL/6J * C57BL/6N
Early innervation defects in Srrm4tm1b(EUCOMM)Wtsi/Srrm4tm1b(EUCOMM)Wtsi embryosSrrm4tm1b(EUCOMM)Wtsi/Srrm4tm1b(EUCOMM)Wtsiinvolves: C57BL/6J * C57BL/6N

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
11/19/2024
MGI 6.24
The Jackson Laboratory