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Phenotype Images associated with this Allele
Nomenclature
Symbol: Srrm4tm1b(EUCOMM)Wtsi
Name: serine/arginine repetitive matrix 4; targeted mutation 1b, Wellcome Trust Sanger Institute
MGI ID: MGI:5752029
Synonyms: nSR100delta7-8
Images for
Allele
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Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Impaired neurite outgrowth of Srrm4tm1b(EUCOMM)Wtsi/Srrm4tm1b(EUCOMM)Wtsi motor neuronsSrrm4tm1b(EUCOMM)Wtsi/Srrm4tm1b(EUCOMM)Wtsiinvolves: C57BL/6J * C57BL/6N
Srrm4tm1b(EUCOMM)Wtsi/Srrm4tm1b(EUCOMM)Wtsi mice display aberrant cortical layering and premature neurogenesisSrrm4tm1b(EUCOMM)Wtsi/Srrm4tm1b(EUCOMM)Wtsiinvolves: C57BL/6J * C57BL/6N
Midline crossing defects in Srrm4tm1b(EUCOMM)Wtsi/Srrm4tm1b(EUCOMM)Wtsi miceSrrm4tm1b(EUCOMM)Wtsi/Srrm4tm1b(EUCOMM)Wtsiinvolves: C57BL/6J * C57BL/6N
Primary hippocampal neurons from Srrm4tm1b(EUCOMM)Wtsi/Srrm4tm1b(EUCOMM)Wtsi mice show reduced neurite lengthSrrm4tm1b(EUCOMM)Wtsi/Srrm4tm1b(EUCOMM)Wtsiinvolves: C57BL/6J * C57BL/6N
Defective sprouting of secondary neurites but not the formation of neuromuscular junctions in Srrm4tm1b(EUCOMM)Wtsi/Srrm4tm1b(EUCOMM)Wtsi miceSrrm4tm1b(EUCOMM)Wtsi/Srrm4tm1b(EUCOMM)Wtsiinvolves: C57BL/6J * C57BL/6N
Early innervation defects in Srrm4tm1b(EUCOMM)Wtsi/Srrm4tm1b(EUCOMM)Wtsi embryosSrrm4tm1b(EUCOMM)Wtsi/Srrm4tm1b(EUCOMM)Wtsiinvolves: C57BL/6J * C57BL/6N

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/29/2024
MGI 6.24
The Jackson Laboratory