Phenotype Images associated with this Allele - MGI

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Phenotype Images associated with this Allele

Nomenclature

Symbol:	Fen1^tm3.1Bhsh
Name:	flap structure specific endonuclease 1; targeted mutation 3.1, Binghui Shen
MGI ID:	MGI:5767323
Synonyms:	E160D, Fen1^ED

Images for
Allele

Click images for details

Image	Caption	Genotypes involving this allele
Image	Caption	Allelic Composition	Genetic Background
	(a) Accumulation of apoptotic nuclei in Fen1^tm3.1Bhsh/Fen1^tm3.1Bhsh tissues	Fen1^tm3.1Bhsh/Fen1^tm3.1Bhsh	Not Specified
	Deposition of IgG immune complex onto the glomeruli and capillary walls of the kidneys and onto cells in the lungs of Fen1^tm3.1Bhsh/Fen1^tm3.1Bhsh mice	Fen1^tm3.1Bhsh/Fen1^tm3.1Bhsh	Not Specified
	Fen1^tm3.1Bhsh/Fen1^tm3.1Bhsh mice are highly susceptible to cancers as a result of their mutator phenotype and chronic inflammation	Fen1^tm3.1Bhsh/Fen1^tm3.1Bhsh	Not Specified
	Fen1^tm3.1Bhsh/Fen1^tm3.1Bhsh mice develop subcutaneous inflammation, lymphoproliferative disorder, and extramedular hematopoiesis	Fen1^tm3.1Bhsh/Fen1^tm3.1Bhsh	Not Specified

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