Phenotype Images associated with this Allele - MGI

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Phenotype Images associated with this Allele

Nomenclature

Symbol:	Polr1a^{tm1b(EUCOMM)Hmgu}
Name:	polymerase (RNA) I polypeptide A; targeted mutation 1b, Helmholtz Zentrum Muenchen GmbH
MGI ID:	MGI:5810733
Synonyms:	Polr1a^-

Images for
Allele

Click images for details

Image	Caption	Genotypes involving this allele
		Allelic Composition	Genetic Background
	Polr1a^{tm1b(EUCOMM)Hmgu}/Polr1a^{tm1b(EUCOMM)Hmgu} mice exhibit embryonic lethality, with only 3% of embryos recovered at E3.5 as dying 2-cell stage embryos, suggesting zygotic genome activation failure.	Polr1a^{tm1b(EUCOMM)Hmgu}/Polr1a^{tm1b(EUCOMM)Hmgu}	C57BL/6N-Polr1a^{tm1b(EUCOMM)Hmgu}/Bay

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