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Phenotype Images associated with this Allele
Nomenclature
Symbol: Hlcsem1(IMPC)J
Name: holocarboxylase synthetase (biotin- [propriony-Coenzyme A-carboxylase (ATP-hydrolysing)] ligase); endonuclease-mediated mutation 1, Jackson
MGI ID: MGI:5817955
Synonyms: Hlcs-, Hlcsem1J
Images for
Allele
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Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Hlcsem1(IMPC)J/Hlcsem1(IMPC)J mice exhibit embryonic lethality. Embryos are recovered at E7.5 but arrest prior to gastrulation and no embryos are seen at E9.5. Embryos are smaller and form a rudimentary egg cylinder but no primitive streak or gastrulation are seen at E7.5.Hlcsem1(IMPC)J/Hlcsem1(IMPC)JC57BL/6NJ-Hlcsem1(IMPC)J/Mmjax

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory