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Phenotype Images associated with this Allele
Nomenclature
Symbol: Spdyatm1.1Klad
Name: speedy/RINGO cell cycle regulator family, member A; targeted mutation 1.1, Phillip Kladis
MGI ID: MGI:5888863
Synonyms: Spdya-, Spdyatm1.1Kliu
Images for
Allele
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Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Depletion of male and female germ cells in Spdyatm1.1Klad/Spdyatm1.1Klad miceSpdyatm1.1Klad/Spdyatm1.1Kladinvolves: 129S1/Sv * C57BL/6J
Impaired telomere attachment to the nuclear envelope and telomere cap exchange in Spdyatm1.1Klad/Spdyatm1.1Klad miceSpdyatm1.1Klad/Spdyatm1.1Kladinvolves: 129S1/Sv * C57BL/6J
Homologous synapsis, DNA double strand break repair, homologous recombination, and telomere tethering to the linker of nucleoskeleton and cytoskeleton complex are impaired in Spdyatm1.1Klad/Spdyatm1.1Klad spermatocytesSpdyatm1.1Klad/Spdyatm1.1Kladinvolves: 129S1/Sv * C57BL/6J
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory