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Phenotype Images associated with this Allele
Nomenclature
Symbol: Polr1dem1(IMPC)J
Name: polymerase (RNA) I polypeptide D; endonuclease-mediated mutation 1, Jackson
MGI ID: MGI:5904258
Synonyms: Polr1d-
Images for
Allele
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Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Polr1dem1(IMPC)J/Polr1dem1(IMPC)J mice exhibit embryonic lethality, with embryos recovered at E3.5 but not at E7.5. Embryos at E3.5 appear as compacted morula. Morulas fail to hatch from the zona pellucida with apparent cell death and never reach blastocyst stage in culture.Polr1dem1(IMPC)J/Polr1dem1(IMPC)JC57BL/6NJ-Polr1dem1(IMPC)J/Mmjax

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/19/2024
MGI 6.24
The Jackson Laboratory