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Phenotype Images associated with this Gene
Symbol
Name
ID
Cdkn2a
cyclin dependent kinase inhibitor 2A
MGI:104738


8 phenotype image(s) for Cdkn2a alleles
Showing image(s) 1 to 8

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Click on allele symbol for full phenotype details.

Caption: Pancreatic tumors in Krastm4Tyj/Krastm4Tyj Trim33tm1Los/Trim33tm1Los Tg(Pdx1-cre)89.1Dam/0 and Krastm4Tyj/Krastm4Tyj Cdkn2atm4Rdp/Cdkn2atm4Rdp Tg(Pdx1-cre)89.1Dam/0 mice (details)
Represented Alleles:
Cdkn2atm4Rdp, cyclin dependent kinase inhibitor 2A; targeted mutation 4, Ronald DePinho
Krastm4Tyj, Kirsten rat sarcoma viral oncogene homolog; targeted mutation 4, Tyler Jacks
Tg(Pdx1-cre)89.1Dam, transgene insertion 89.1, Douglas A Melton
Trim33tm1Los, tripartite motif-containing 33; targeted mutation 1, Regine Losson
Copyright: This image is from Vincent DF, PLoS Genet 2009 Jul;5(7):e1000575, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:151781
Caption: Degenerative phenotypes, including increased apoptosis in gastrointestinal crypts and germ cell depletion, in Terctm1Rdp/Terctm1Rdp and Cdkn2atm1Rdp/Cdkn2atm1Rdp Terctm1Rdp/Terctm1Rdp mice (details)
Represented Alleles:
Cdkn2atm1Rdp, cyclin dependent kinase inhibitor 2A; targeted mutation 1, Ronald DePinho
Terctm1Rdp, telomerase RNA component; targeted mutation 1, Ronald DePinho
Copyright: This image is from Khoo CM, Proc Natl Acad Sci U S A 2007 Mar 6;104(10):3931-6. Copyright 2007 National Academy of Sciences, U.S.A. J:120065
Caption: Metastasis of primary squamous cell carcinoma to lymph nodes and lungs in Cdkn2atm1Cjs/Cdkn2atm1Cjs mice (details)
Represented Alleles:
Cdkn2atm1Cjs, cyclin dependent kinase inhibitor 2A; targeted mutation 1, Charles J Scherr
Copyright: This image is from Kelly-Spratt KS, PLoS Biol 2004 Sep;2(8):E242, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:93298
Caption: Tumor multiplicity and proliferation index in Cdkn2atm1Cjs/Cdkn2atm1Cjs, Trp53tm1Brd/Trp53tm1Brd and Cdkn2atm1Cjs/Cdkn2atm1Cjs Trp53tm1Brd/Trp53tm1Brd mice (details)
Represented Alleles:
Cdkn2atm1Cjs, cyclin dependent kinase inhibitor 2A; targeted mutation 1, Charles J Scherr
Trp53tm1Brd, transformation related protein 53; targeted mutation 1, Allan Bradley
Copyright: This image is from Kelly-Spratt KS, PLoS Biol 2004 Sep;2(8):E242, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:93298
Caption: Abnormal retrolental tissue present in the eyes of neonatal Cdkn2atm1Cjs/Cdkn2atm1Cjs mice (details)
Represented Alleles:
Cdkn2atm1Cjs, cyclin dependent kinase inhibitor 2A; targeted mutation 1, Charles J Scherr
Copyright: This image is from McKeller RN, Proc Natl Acad Sci U S A 2002 Mar 19;99(6):3848-53. Copyright 2002 National Academy of Sciences, U.S.A. J:75215
Caption: Retrolental tissue in Cdkn2atm1Cjs/Cdkn2atm1Cjs mice contains mature hyaloid vascular structures and endothelial cells (details)
Represented Alleles:
Cdkn2atm1Cjs, cyclin dependent kinase inhibitor 2A; targeted mutation 1, Charles J Scherr
Copyright: This image is from McKeller RN, Proc Natl Acad Sci U S A 2002 Mar 19;99(6):3848-53. Copyright 2002 National Academy of Sciences, U.S.A. J:75215
Caption: PHPV-like abnormalities develop in Cdkn2atm1Cjs/Cdkn2atm1Cjs mouse eyes (details)
Represented Alleles:
Cdkn2atm1Cjs, cyclin dependent kinase inhibitor 2A; targeted mutation 1, Charles J Scherr
Copyright: This image is from McKeller RN, Proc Natl Acad Sci U S A 2002 Mar 19;99(6):3848-53. Copyright 2002 National Academy of Sciences, U.S.A. J:75215
Caption: Persistent hyperplastic primary vitreous (PHPV) in Cdkn2atm1Cjs/Cdkn2atm1Cjs mice is p53 independent (details)
Represented Alleles:
Cdkn2atm1Cjs, cyclin dependent kinase inhibitor 2A; targeted mutation 1, Charles J Scherr
Trp53tm1Tyj, transformation related protein 53; targeted mutation 1, Tyler Jacks
Copyright: This image is from McKeller RN, Proc Natl Acad Sci U S A 2002 Mar 19;99(6):3848-53. Copyright 2002 National Academy of Sciences, U.S.A. J:75215

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory