Symbol Name ID |
Ephb4
Eph receptor B4 MGI:104757 |
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Caption: Mutant 2412-003-2 (E15.5) presents with parallel outflow tracts suggesting overriding aorta. Also observed is premature constriction of the patent ductus.
(details)
Represented Alleles:
Ephb4b2b2412Clo,
Eph receptor B4; Bench to Bassinet Program (B2B/CVDC), mutation 2412 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors.
J:175213
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Caption: EFIC Summary
(details)
Represented Alleles:
Ephb4b2b2412Clo,
Eph receptor B4; Bench to Bassinet Program (B2B/CVDC), mutation 2412 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors.
J:175213
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Caption: Serial 2D ECM image stack in the coronal plane of 2412-003-2 (E15.5) shows perimembranous VSD, overriding aorta, hypoplastic PA, aberrant right subclavian artery forming incomplete vascular ring
Click thumbnail to play movie. (details) Represented Alleles:
Ephb4b2b2412Clo,
Eph receptor B4; Bench to Bassinet Program (B2B/CVDC), mutation 2412 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors.
J:175213
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Caption: Color flow spectral Doppler imaging of mutant 2412-003 (E15.5) in the transverse view shows shunting between LV and RV, suggesting VSD.
Click thumbnail to play movie. (details) Represented Alleles:
Ephb4b2b2412Clo,
Eph receptor B4; Bench to Bassinet Program (B2B/CVDC), mutation 2412 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors.
J:175213
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Caption: Mutant 2412-003-2 (E15.5) exhibits cystic kidneys, and hydronephrosis confirmed by histology.
(details)
Represented Alleles:
Ephb4b2b2412Clo,
Eph receptor B4; Bench to Bassinet Program (B2B/CVDC), mutation 2412 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors.
J:175213
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Caption: Kidneys of mutant 2412-003-2 show severe cystic kidney disease.
(details)
Represented Alleles:
Ephb4b2b2412Clo,
Eph receptor B4; Bench to Bassinet Program (B2B/CVDC), mutation 2412 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors.
J:175213
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Caption: Mutant 2412-002-2 (E15.5) shows a pulmonary artery that is displaced suggesting overriding aorta, which is confirmed by ECM imaging.
(details)
Represented Alleles:
Ephb4b2b2412Clo,
Eph receptor B4; Bench to Bassinet Program (B2B/CVDC), mutation 2412 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors.
J:175213
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Caption: EFIC Summary
(details)
Represented Alleles:
Ephb4b2b2412Clo,
Eph receptor B4; Bench to Bassinet Program (B2B/CVDC), mutation 2412 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors.
J:175213
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Caption: Serial 2D ECM image stack in the coronal plane of 2412-002-2 (E15.5) reveals perimembranous VSD and overriding aorta.
Click thumbnail to play movie. (details) Represented Alleles:
Ephb4b2b2412Clo,
Eph receptor B4; Bench to Bassinet Program (B2B/CVDC), mutation 2412 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors.
J:175213
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Caption: Mutant 2412-002-2 (E15.5) presents with hydronephrosis.
(details)
Represented Alleles:
Ephb4b2b2412Clo,
Eph receptor B4; Bench to Bassinet Program (B2B/CVDC), mutation 2412 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors.
J:175213
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 12/17/2024 MGI 6.24 |
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