Phenotype Images associated with this Gene

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Phenotype Images associated with this Gene

Symbol
Name
ID

Myo5b
myosin VB
MGI:106598

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Click on allele symbol for full phenotype details.

	Caption: Wrinkled skin and evidence of diarrhea in Myo5b^{tm1a(KOMP)Wtsi}/Myo5b^{tm1a(KOMP)Wtsi} newborns (details) Represented Alleles: Myo5b^{tm1a(KOMP)Wtsi}, myosin VB; targeted mutation 1a, Wellcome Trust Sanger Institute Myo5b^{tm1a(KOMP)Wtsi}, myosin VB; targeted mutation 1a, Wellcome Trust Sanger Institute Copyright: This image is from Carton-Garcia F, Sci Rep 2015;5():12312, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:229427
	Caption: Ultrastructural defects in the intestinal epithelium of Myo5b^{tm1a(KOMP)Wtsi}/Myo5b^{tm1a(KOMP)Wtsi} E20 embryos (details) Represented Alleles: Myo5b^{tm1a(KOMP)Wtsi}, myosin VB; targeted mutation 1a, Wellcome Trust Sanger Institute Myo5b^{tm1a(KOMP)Wtsi}, myosin VB; targeted mutation 1a, Wellcome Trust Sanger Institute Copyright: This image is from Carton-Garcia F, Sci Rep 2015;5():12312, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:229427
	Caption: Shorter microvilli and a subapical region lacking microvesicle trafficking in Myo5b^{tm1a(KOMP)Wtsi}/Myo5b^{tm1a(KOMP)Wtsi} enterocytes (details) Represented Alleles: Myo5b^{tm1a(KOMP)Wtsi}, myosin VB; targeted mutation 1a, Wellcome Trust Sanger Institute Myo5b^{tm1a(KOMP)Wtsi}, myosin VB; targeted mutation 1a, Wellcome Trust Sanger Institute Copyright: This image is from Carton-Garcia F, Sci Rep 2015;5():12312, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:229427
	Caption: Microvillus inclusion disease phenotype in Myo5b^tm1.1Cle/Myo5b^tm1.1Cle Tg(Vil1-cre/ERT2)23Syr/0 mice (details) Represented Alleles: Myo5b^tm1.1Cle, myosin VB; targeted mutation 1.1, Hans Clevers Tg(Vil1-cre/ERT2)23Syr, transgene insertion 23, Sylvie Robine Copyright: This image is from Schneeberger K, Proc Natl Acad Sci U S A 2015 Oct 6;112(40):12408-13. Copyright 2015 National Academy of Sciences, U.S.A. J:227079
	Caption: Lower villus cells are the first cells affected in Myo5b^tm1.1Cle/Myo5b^tm1.1Cle/ Tg(Vil1-cre/ERT2)23Syr/0 mice, showing accumulation of vesicles and widened intercellular spaces (details) Represented Alleles: Myo5b^tm1.1Cle, myosin VB; targeted mutation 1.1, Hans Clevers Tg(Vil1-cre/ERT2)23Syr, transgene insertion 23, Sylvie Robine Copyright: This image is from Schneeberger K, Proc Natl Acad Sci U S A 2015 Oct 6;112(40):12408-13. Copyright 2015 National Academy of Sciences, U.S.A. J:227079

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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