|
Symbol Name ID |
Ctsk
cathepsin K MGI:107823 |
|
|
Caption: 3-week-old Ctsktm1(cre)Ska/Ctsktm1(cre)Ska Snx10tm1c(EUCOMM)Raba/Snx10tm1c(EUCOMM)Raba mice are growth retarded, have a tooth eruption defect, and are osteopetrotic
(details)
Represented Alleles:
Ctsktm1(cre)Ska,
cathepsin K; targeted mutation 1, Shigeaki Kato
Snx10tm1c(EUCOMM)Raba,
sorting nexin 10; targeted mutation 1c, Ricardo A Battaglino
Copyright: This image is from Ye L, PLoS Genet 2015 Mar;11(3):e1005057, and is displayed under the terms of the Creative Commons Attribution 4.0 International License.
J:224711
|
|
|
Caption: Bone abnormalities in Snx10tm1c(EUCOMM)Raba/Snx10tm1c(EUCOMM)Raba Ctsktm1(cre)Ska/Ctsktm1(cre)Ska and Snx10tm1a(EUCOMM)Raba/Snx10tm1a(EUCOMM)Raba mice
(details)
Represented Alleles:
Ctsktm1(cre)Ska,
cathepsin K; targeted mutation 1, Shigeaki Kato
Snx10tm1a(EUCOMM)Raba,
sorting nexin 10; targeted mutation 1a, Ricardo A Battaglino
Snx10tm1c(EUCOMM)Raba,
sorting nexin 10; targeted mutation 1c, Ricardo A Battaglino
Copyright: This image is from Ye L, PLoS Genet 2015 Mar;11(3):e1005057, and is displayed under the terms of the Creative Commons Attribution 4.0 International License.
J:224711
|
|
|
Caption: Low bone mass in Cthrc1tm1.1Suna/Cthrc1tm1.1Suna Ctsktm1(cre)Ska/Ctsk+ mice
(details)
Represented Alleles:
Cthrc1tm1.1Suna,
collagen triple helix repeat containing 1; targeted mutation 1.1, Sunao Takeshita
Ctsktm1(cre)Ska,
cathepsin K; targeted mutation 1, Shigeaki Kato
Copyright: This image is from Takeshita S, J Clin Invest 2013 Sep 3;123(9):3914-24 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright.
J:201631
|
|
|
Caption: Increase in cancellous bone mass in Ctsktm1.1Rbar/Ctsktm1.1Rbar Tg(Mx1-cre)1Cgn/0 and Ctsktm1.1Rbar/Ctsktm1.1Rbar Tg(Itgam-cre)AJva/0 mice
(details)
Represented Alleles:
Ctsktm1.1Rbar,
cathepsin K; targeted mutation 1.1, Roland Baron
Tg(Itgam-cre)AJva,
transgene insertion A, Jean Vacher
Tg(Mx1-cre)1Cgn,
transgene insertion 1, University of Cologne
Copyright: This image is from Lotinun S, J Clin Invest 2013 Jan 16;(): and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright.
J:194492
|
|
|
Caption: Increase in cancellous bone mass in Ctsktm1.1Rbar/Ctsktm1.1Rbar Tg(Mx1-cre)1Cgn/0 and Ctsktm1.1Rbar/Ctsktm1.1Rbar Tg(Itgam-cre)AJva/0 femurs
(details)
Represented Alleles:
Ctsktm1.1Rbar,
cathepsin K; targeted mutation 1.1, Roland Baron
Copyright: This image is from Lotinun S, J Clin Invest 2013 Jan 16;(): and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright.
J:194492
|
|
|
Caption: Increase in TRAP-positive osteoclasts in Ctsktm1.1Rbar/Ctsktm1.1Rbar Tg(Mx1-cre)1Cgn/0 mice in vitro
(details)
Represented Alleles:
Ctsktm1.1Rbar,
cathepsin K; targeted mutation 1.1, Roland Baron
Copyright: This image is from Lotinun S, J Clin Invest 2013 Jan 16;(): and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright.
J:194492
|
|
|
Caption: Increase in cross-sectional bone volume and cortical bone volume in Ctsktm1.1Rbar/Ctsktm1.1Rbar Tg(Itgam-cre)AJva/0 femurs but not in Ctsktm1.1Rbar/Ctsktm1.1Rbar Tg(Mx1-cre)1Cgn/0 or Ctsktm1.1Rbar/Ctsktm1.1Rbar Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0 femurs
(details)
Represented Alleles:
Ctsktm1.1Rbar,
cathepsin K; targeted mutation 1.1, Roland Baron
Tg(Itgam-cre)AJva,
transgene insertion A, Jean Vacher
Tg(Mx1-cre)1Cgn,
transgene insertion 1, University of Cologne
Tg(Sp7-tTA,tetO-EGFP/cre)1Amc,
transgene insertion 1, Andrew P McMahon
Copyright: This image is from Lotinun S, J Clin Invest 2013 Jan 16;(): and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright.
J:194492
|
|
|
Caption: Clubbing of the long bones with increased trabecular bone volume in Slc4a2tm2Ges/Slc4a2tm2Ges Ctsktm1(cre)Ska/Ctsk+ mice
(details)
Represented Alleles:
Ctsktm1(cre)Ska,
cathepsin K; targeted mutation 1, Shigeaki Kato
Slc4a2tm2Ges,
solute carrier family 4 (anion exchanger), member 2; targeted mutation 2, Gary E Shull
Copyright: This image is from Coury F, Proc Natl Acad Sci U S A 2013 Feb 5;110(6):2163-8. Copyright 2013 National Academy of Sciences, U.S.A.
J:193823
|
|
|
Caption: Radiographs and histological analysis of Ctsktm1Psa/Ctsktm1Psa mice
(details)
Represented Alleles:
Ctsktm1Psa,
cathepsin K; targeted mutation 1, Paul Saftig
Copyright: This image is from Saftig P, Proc Natl Acad Sci U S A 1998 Nov 10;95(23):13453-8. Copyright 1998 National Academy of Sciences, U.S.A.
J:50934
|
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
||
|
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support. |
last database update 11/12/2024 MGI 6.24 |
|
|
|
||
Analysis Tools