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Phenotype Images associated with this Gene
Symbol
Name
ID
Ctsk
cathepsin K
MGI:107823


9 phenotype image(s) for Ctsk alleles
Showing image(s) 1 to 9

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Click on allele symbol for full phenotype details.

Caption: 3-week-old Ctsktm1(cre)Ska/Ctsktm1(cre)Ska Snx10tm1c(EUCOMM)Raba/Snx10tm1c(EUCOMM)Raba mice are growth retarded, have a tooth eruption defect, and are osteopetrotic (details)
Represented Alleles:
Ctsktm1(cre)Ska, cathepsin K; targeted mutation 1, Shigeaki Kato
Snx10tm1c(EUCOMM)Raba, sorting nexin 10; targeted mutation 1c, Ricardo A Battaglino
Copyright: This image is from Ye L, PLoS Genet 2015 Mar;11(3):e1005057, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:224711
Caption: Bone abnormalities in Snx10tm1c(EUCOMM)Raba/Snx10tm1c(EUCOMM)Raba Ctsktm1(cre)Ska/Ctsktm1(cre)Ska and Snx10tm1a(EUCOMM)Raba/Snx10tm1a(EUCOMM)Raba mice (details)
Represented Alleles:
Ctsktm1(cre)Ska, cathepsin K; targeted mutation 1, Shigeaki Kato
Snx10tm1a(EUCOMM)Raba, sorting nexin 10; targeted mutation 1a, Ricardo A Battaglino
Snx10tm1c(EUCOMM)Raba, sorting nexin 10; targeted mutation 1c, Ricardo A Battaglino
Copyright: This image is from Ye L, PLoS Genet 2015 Mar;11(3):e1005057, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:224711
Caption: Low bone mass in Cthrc1tm1.1Suna/Cthrc1tm1.1Suna Ctsktm1(cre)Ska/Ctsk+ mice (details)
Represented Alleles:
Cthrc1tm1.1Suna, collagen triple helix repeat containing 1; targeted mutation 1.1, Sunao Takeshita
Ctsktm1(cre)Ska, cathepsin K; targeted mutation 1, Shigeaki Kato
Copyright: This image is from Takeshita S, J Clin Invest 2013 Sep 3;123(9):3914-24 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:201631
Caption: Increase in cancellous bone mass in Ctsktm1.1Rbar/Ctsktm1.1Rbar Tg(Mx1-cre)1Cgn/0 and Ctsktm1.1Rbar/Ctsktm1.1Rbar Tg(Itgam-cre)AJva/0 mice (details)
Represented Alleles:
Ctsktm1.1Rbar, cathepsin K; targeted mutation 1.1, Roland Baron
Tg(Itgam-cre)AJva, transgene insertion A, Jean Vacher
Tg(Mx1-cre)1Cgn, transgene insertion 1, University of Cologne
Copyright: This image is from Lotinun S, J Clin Invest 2013 Jan 16;(): and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:194492
Caption: Increase in cancellous bone mass in Ctsktm1.1Rbar/Ctsktm1.1Rbar Tg(Mx1-cre)1Cgn/0 and Ctsktm1.1Rbar/Ctsktm1.1Rbar Tg(Itgam-cre)AJva/0 femurs (details)
Represented Alleles:
Ctsktm1.1Rbar, cathepsin K; targeted mutation 1.1, Roland Baron
Copyright: This image is from Lotinun S, J Clin Invest 2013 Jan 16;(): and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:194492
Caption: Increase in TRAP-positive osteoclasts in Ctsktm1.1Rbar/Ctsktm1.1Rbar Tg(Mx1-cre)1Cgn/0 mice in vitro (details)
Represented Alleles:
Ctsktm1.1Rbar, cathepsin K; targeted mutation 1.1, Roland Baron
Copyright: This image is from Lotinun S, J Clin Invest 2013 Jan 16;(): and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:194492
Caption: Increase in cross-sectional bone volume and cortical bone volume in Ctsktm1.1Rbar/Ctsktm1.1Rbar Tg(Itgam-cre)AJva/0 femurs but not in Ctsktm1.1Rbar/Ctsktm1.1Rbar Tg(Mx1-cre)1Cgn/0 or Ctsktm1.1Rbar/Ctsktm1.1Rbar Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0 femurs (details)
Represented Alleles:
Ctsktm1.1Rbar, cathepsin K; targeted mutation 1.1, Roland Baron
Tg(Itgam-cre)AJva, transgene insertion A, Jean Vacher
Tg(Mx1-cre)1Cgn, transgene insertion 1, University of Cologne
Tg(Sp7-tTA,tetO-EGFP/cre)1Amc, transgene insertion 1, Andrew P McMahon
Copyright: This image is from Lotinun S, J Clin Invest 2013 Jan 16;(): and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:194492
Caption: Clubbing of the long bones with increased trabecular bone volume in Slc4a2tm2Ges/Slc4a2tm2Ges Ctsktm1(cre)Ska/Ctsk+ mice (details)
Represented Alleles:
Ctsktm1(cre)Ska, cathepsin K; targeted mutation 1, Shigeaki Kato
Slc4a2tm2Ges, solute carrier family 4 (anion exchanger), member 2; targeted mutation 2, Gary E Shull
Copyright: This image is from Coury F, Proc Natl Acad Sci U S A 2013 Feb 5;110(6):2163-8. Copyright 2013 National Academy of Sciences, U.S.A. J:193823
Caption: Radiographs and histological analysis of Ctsktm1Psa/Ctsktm1Psa mice (details)
Represented Alleles:
Ctsktm1Psa, cathepsin K; targeted mutation 1, Paul Saftig
Copyright: This image is from Saftig P, Proc Natl Acad Sci U S A 1998 Nov 10;95(23):13453-8. Copyright 1998 National Academy of Sciences, U.S.A. J:50934

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory