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Phenotype Images associated with this Gene
Symbol
Name
ID 		Timp4
tissue inhibitor of metalloproteinase 4
MGI:109125


3 phenotype image(s) for Timp4 alleles
Showing image(s) 1 to 3
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Click on allele symbol for full phenotype details.

Caption: Cardiac rupture, decreased collagen synthesis, and disruption of collagen network in Timp4tm1Vuo/Timp4tm1Vuo hearts after myocardial infarction (details)
Represented Alleles:
Timp4tm1Vuo, tissue inhibitor of metalloproteinase 4; targeted mutation 1, Eero Vuorio
Copyright: This image is from Koskivirta I, J Biol Chem 2010 Aug 6;285(32):24487-93 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:165901
Caption: Increased neutrophil accumulation in Timp4tm1Vuo/Timp4tm1Vuo hearts at 3 days post-myocardial infarction (details)
Represented Alleles:
Timp4tm1Vuo, tissue inhibitor of metalloproteinase 4; targeted mutation 1, Eero Vuorio
Copyright: This image is from Koskivirta I, J Biol Chem 2010 Aug 6;285(32):24487-93 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:165901
Caption: Cardiac neutrophil accumulation post-myocardial infraction is normalized in Timp4tm1Vuo/Timp4tm1Vuo Mmp2tm1Ito/Mmp2tm1Ito mice (details)
Represented Alleles:
Mmp2tm1Ito, matrix metallopeptidase 2; targeted mutation 1, Shigeyoshi Itohara
Timp4tm1Vuo, tissue inhibitor of metalloproteinase 4; targeted mutation 1, Eero Vuorio
Copyright: This image is from Koskivirta I, J Biol Chem 2010 Aug 6;285(32):24487-93 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:165901
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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11/12/2024
MGI 6.24 		The Jackson Laboratory